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Clinical Course and Predictors of Biologic Therapy, Hospitalisation and Surgery: A Five‐Year Prospective Study in Newly Diagnosed Inflammatory Bowel Disease

Alimentary Pharmacology &Therapeutics, EarlyView.
In this large multicentre Spanish inception cohort, biologics/JAK inhibitors were frequently used during the first 5 years after inflammatory bowel disease diagnosis and were associated with reduced hospitalisation risk, although not with lower abdominal surgery rates.
Ana Garre +308 more
wiley +1 more source

Exploring Use‐Wear Texture Quantification Through Confocal Microscopy on Tools Made From Volcanic Rocks (Basalt and Phonolite)

Archaeometry, EarlyView.
ABSTRACT Functional analysis is essential for reconstructing lithic tool use. Recent approaches combining confocal microscopy and surface texture analysis provide quantitative alternatives to traditional visual use‐wear analysis, although their application to coarse‐grained, heterogeneous rocks remains challenging because of their complex surface ...
Idaira Brito‐Abrante +2 more
wiley +1 more source

Hybrid Galam-Bass Model for Technology Innovation. [PDF]

Entropy (Basel)
Rotundo G +5 more
europepmc +1 more source

Functional assessment of inherited myeloid neoplasm‐associated SAMD9L germline variants via Monoallelic CRISPR modelling

British Journal of Haematology, EarlyView.
Summary While the majority of myeloid neoplasms are sporadic, the increasing application of germline genetic testing has led the World Health Organization to designate ‘Myeloid malignancies with germline predisposition’ as a distinct clinical entity, carrying major implications for clinical care and research.
Elena Vuelta +9 more
wiley +1 more source

Predicting the Intention to Use Generative Artificial Intelligence for Health Information: Comparative Survey Study. [PDF]

J Med Internet Res
Matthes J +8 more
europepmc +1 more source

Olfactory proteomics reveals the capacity of the HDAC1 inhibitor pyroxamide to halt the α‐synuclein preformed fibrils‐induced damage in nasal epithelial, microglial and dopaminergic neuronal cell lines

Brain Pathology, EarlyView.
Omics‐driven drug repositioning reveals pyroxamide as a neuroprotective HDAC1 inhibitor in Parkinson's disease models. Abstract Parkinson's disease (PD) is the second most common neurodegenerative disorder mainly characterized by the degeneration of dopaminergic neurons originating in the substantia nigra (SN) pars compacta and projecting to other ...
Paz Cartas‐Cejudo +7 more
wiley +1 more source

Increasing trend of scabies in Belgium, 2000-2023. [PDF]

Arch Public Health
Laisnez V +16 more
europepmc +1 more source

A Territorial Approach to Transitioning Oil and Gas Producing Regions: Comparative Practices and Prospects for Canada

Canadian Public Administration, EarlyView.
Abstract Oil and gas transitions are relatively new and especially difficult because the sector is large, economically central, and deeply embedded in national energy systems. Territorial approaches—grounded in regional political economies, institutions, and community impacts—offer a politically feasible way to begin meaningful oil and gas transitions ...
Tamara Krawchenko, Sophie Kiernan
wiley +1 more source

Towards Common Ground: Perspectives on Energy Transitions in Canadian Oil and Gas Producing Municipalities

Canadian Public Administration, EarlyView.
Abstract Oil and gas producing municipalities host Canada's highest‐emitting industries while facing economic and social risks as the country pursues carbon neutrality. Understanding how these communities envision their economic futures, and the barriers and enablers they encounter in pursuing low‐carbon opportunities, can inform decision‐makers ...
Rowan Hargreaves, Ekaterina Rhodes, Tamara Krawchenko +2 more
wiley +1 more source

Faire avancer les soins climatiques dans les soins de santé : feu vert au secteur de la pharmacie. [PDF]

Can J Hosp Pharm
MacLaren R.
europepmc +1 more source

8. economic growth
1. no poverty
animal culture

business
9. industry and infrastructure
12. responsible consumption

economics
new economy
2. zero hunger