Results 41 to 50 of about 4,884,628 (369)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

European Traffic Connections and Croatia

open access: yesPromet (Zagreb), 2012
The overall traffic connections within Europe are particularlyimportant from the economic point of view of eve1y Europeancountry. Therefore, the development of traffic and trafficinfrastructure in the European Union are considered with specialattention ...
Ivan Vuković, Ana Vizjak
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Big Data based Research on Mechanisms of Sharing Economy Restructuring the World [PDF]

open access: yesarXiv, 2020
Many researches have discussed the phenomenon and definition of sharing economy, but an understanding of sharing economy's reconstructions of the world remains elusive. We illustrate the mechanism of sharing economy's reconstructions of the world in detail based on big data including the mechanism of sharing economy's reconstructions of society, time ...
arxiv  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

INNOVATION IN THE WINTER ROAD MAINTENANCE AND ITSECONOMIC JUSTIFICATION [PDF]

open access: yesTransport Problems, 2020
In general, it can be presentedthat winter road maintenance costs are rising due to increasing mobility, rising of salaries,and technologicalneeds. For this reason, it is necessary to bring innovations intothese processes.
Stefan SEDIVY   +4 more
doaj   +1 more source

On the minimal simplex economy [PDF]

open access: yesarXiv, 2023
In our previous paper we proved that every affine economy has a competitive equilibrium. We define a simplex economy as an affine economy consisting of a stochastic allocation (defining the initial endowments) and a variation with repetition of the number of commodities taking the number of consumers (representing the preferences).
arxiv  

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

open access: yesMolecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns   +4 more
wiley   +1 more source

Study on Some Aspects of the Economic and Social Impact of the Covid 19 Pandemic [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2021
This paper takes the form of a meta-analysis which aims to underline some aspects identified at international and national levels as a result of the pandemic of the last two years, reflected in the economic and social fields.
Solomia Andres
doaj  

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