Results 51 to 60 of about 6,547,109 (416)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Energy structure, digital economy, and carbon emissions: evidence from China

Environmental science and pollution research international, 2021
As a new production factor, digitalization plays a vital role in society, economy, and the environment. Based on the expanded STIRPAT model, this paper empirically tests the impact of energy structure and digital economy on carbon emissions by panel data
Yan Li, Xiaodong Yang, Qiying Ran, Haitao Wu, M. Irfan, Munir Ahmad   +5 more
semanticscholar   +1 more source

Big Data based Research on Mechanisms of Sharing Economy Restructuring the World [PDF]

arXiv, 2020
Many researches have discussed the phenomenon and definition of sharing economy, but an understanding of sharing economy's reconstructions of the world remains elusive. We illustrate the mechanism of sharing economy's reconstructions of the world in detail based on big data including the mechanism of sharing economy's reconstructions of society, time ...
arxiv  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Innovation and the circular economy: A systematic literature review

Business Strategy and the Environment, 2021
The circular economy emerged as an alternative model to the linear system, which now appears to be reaching its physical limitations. To transition to a circular economy, companies must not only be aware of but also engage in more sustainable practices ...
Nathalia Suchek, C. Fernandes, S. Kraus, Matthias Filser, Helena Sjögrén   +4 more
semanticscholar   +1 more source

EFFECT OF ACCELERATED AGING ON MECHANICAL PROPERTIES AND STRUCTURE OF NANO-SCALE COMPOSITE SYSTEMS [PDF]

, 2011
Nano-scale composites are being investigated by academic, industrial, and national laboratories for potential applications such as wear resistant coatings and high strength foils.
Economy, David
core   +1 more source

On the minimal simplex economy [PDF]

arXiv, 2023
In our previous paper we proved that every affine economy has a competitive equilibrium. We define a simplex economy as an affine economy consisting of a stochastic allocation (defining the initial endowments) and a variation with repetition of the number of commodities taking the number of consumers (representing the preferences).
arxiv  

INNOVATION IN THE WINTER ROAD MAINTENANCE AND ITSECONOMIC JUSTIFICATION [PDF]

Transport Problems, 2020
In general, it can be presentedthat winter road maintenance costs are rising due to increasing mobility, rising of salaries,and technologicalneeds. For this reason, it is necessary to bring innovations intothese processes.
Stefan SEDIVY, Zuzana FLORKOVA, Gabriel GASPAR, Juraj DUDAK, Peter FABO   +4 more
doaj   +1 more source

Study on Some Aspects of the Economic and Social Impact of the Covid 19 Pandemic [PDF]

Ovidius University Annals: Economic Sciences Series, 2021
This paper takes the form of a meta-analysis which aims to underline some aspects identified at international and national levels as a result of the pandemic of the last two years, reflected in the economic and social fields.
Solomia Andres
doaj