Results 91 to 100 of about 165,447 (318)
Insect Science, EarlyView.An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates +4 more
wiley +1 more source
Nucleotide sequence of the EcoRI E fragment of adenovirus 2 genome.
Nucleic Acids Research, 1980 The entire nucleotide sequence of the Ad.2 EcoRI E fragment has been determined using the Maxam and Gilbert method. This sequence of 2222 bp, which maps between coordinate 83.4 and 89.7 contains information relative to the early 3 region and to the fiber
J. Hérissé, F. Galibert
semanticscholar +1 more source
Andrology, EarlyView.Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos +4 more
wiley +1 more source
Repair of the Escherichia coli chromosome after in vivo scission by the EcoRI endonuclease.
Proceedings of the National Academy of Sciences of the United States of America, 1989 We prepared a set of temperature-sensitive mutants of the EcoRI endonuclease. Under semipermissive conditions, Escherichia coli strains bearing these alleles form poorly growing colonies in which intracellular substrates are cleaved at EcoRI sites and ...
Joseph Heitman, N. Zinder, Peter Model
semanticscholar +1 more source
Cancer Science, EarlyView.With the aim of clinical applications, we established a simplified evaluation method for BRCA1 methylation using fragment analysis, called BRCA1‐FAM. We confirmed that high‐grade serous ovarian cancer patients with BRCA1 methylation had poor prognosis.
Saki Tsuchimochi +20 more
wiley +1 more source
Biotecnología Vegetal, 2002 AFLP techniques have been reported to determine the genetic stability at a molecular level of cassava plants propagated by several methods: somatic embryogenesis, organogenesis and field conditions. ‘CMC-76’, ‘CEMSA 74-725’ and ‘Señorita’ clones from the
Víctor R. Medero +6 more
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Cancer‐Type‐Specific DNA Methylation Is a Source of Vulnerability in Liver Cancer Cells
Cancer Science, EarlyView.We profiled genome‐wide DNA methylation in 1165 human cancer cell lines representing 25 cancer types and identified 73 genes as potential liver cancer‐specific methylation‐silenced genes. We selected ASNS, BCAT2, FXYD5, and NQO1 genes for further experimental analysis and demonstrated that aberrant methylation of BCAT2 contributes to the vulnerability ...
Karen Minowa +3 more
wiley +1 more source
Genetics and Molecular Biology, 2002 Human alpha1-acid glycoprotein (AGP) or orosomucoid (ORM) is a major acute phase protein that is thought to play a crucial role in maintaining homeostasis.
Owczarek Catherine M. +2 more
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Cancer Science, EarlyView.Hepatitis B virus (HBV) infection is a major driver of hepatocellular carcinoma (HCC) and is associated with resistance to sorafenib, the first‐line treatment for advanced HCC. This study demonstrates that the small HBV surface antigen (SHBs) promotes sorafenib resistance by activating the RAF1/MEK/ERK signaling pathway, inhibiting apoptosis in HCC ...
Shuxiang Wu +6 more
wiley +1 more source
Construcción de una genoteca de cDNA de fríjol (Phaseolus vulgaris L.) para mapeo genético
Acta Agronómica, 1995 <p>A small cDNA library from beans (Phaseolus vulgaris L.) of about 1500 clones was constructed, to further saturate the bean RFLP linkage map. The primarily synthesized cDNAs were amplified by PCR using the adaptors as primers for amplification ...
Roca William M. +4 more
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