Results 101 to 110 of about 225,565 (329)

Target Binding of Black Phosphorus Nanomaterial to Polo‐Like Kinase 1 for Cancer Chemotherapy: A Mutual Selection of Nanomaterial and Protein

open access: yesExploration, EarlyView.
This study investigates the effect of protein properties on the nanomaterial‐protein interaction and elucidates the molecular mechanisms underlying the targeted inhibition of polo‐like kinase (PLK1) by black phosphorus nanomaterials (BPNMs). The specific targeting inhibition is attributed to the intrinsic properties of both the PLK1 protein and the ...
Fangfang Liu   +15 more
wiley   +1 more source

Identification and nucleotide sequences of mxaA, mxaC, mxaK, mxaL, and mxaD genes from Methylobacterium extorquens AM1 [PDF]

open access: yes, 1995
The DNA sequence for a 4.4-kb HindIII-XhoI Methylobacterium extorquens AM1 DNA fragment that is known to contain three genes (mxaAKL) involved in incorporation of calcium into methanol dehydrogenase (I. W. Richardson and C. Anthony, Biochem. J.
Kim, Young M.   +3 more
core  

The Human Pregnancy-Specific Glycoprotein Genes are Tightly Linked on the Long Arm of Chromosome 19 and are Coordinately Expressed [PDF]

open access: yes, 1990
The pregnancy-specific glycoprotein (PSG) genes encode a group of proteins which are found in large amounts in placenta and maternal serum. In situ hybridization analyses of metaphase chromosomes reveal that all the human pregnancy-specific glycoprotein (
Barnett   +40 more
core   +1 more source

Role of the Choline‐Binding Protein A in the Ability of Porcine Ligilactobacillus salivarius FFIG58 to Modulate TLR3‐Mediated Intestinal Antiviral Immunity

open access: yesFood Frontiers, EarlyView.
The choline‐binding protein A (CbpA) was shown to mediate adhesion of probiotic Ligilactobacillus salivarius strains to human intestinal epithelial cells (IECs). A knockout mutant lacking the CbpA protein derived from the immunomodulatory porcine strain L. salivarius FFIG58 was obtained. The CbpA is a key surface protein of L.
Yoshiya Imamura   +13 more
wiley   +1 more source

Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker. [PDF]

open access: yes, 2011
Most bacteria can only be transformed with circular plasmids, so robust DNA integration methods for these rely upon selection of single-crossover clones followed by counter-selection of double-crossover clones.
Cartman, ST   +6 more
core   +5 more sources

Long Noncoding RNA TOB1‐AS1 Represses Cervical Cancer Cell Proliferation, Invasion, and Migration via the MicroRNA‐27a‐3p/Thioredoxin‐Interacting Protein Molecular Axis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cervical cancer (CC) remains a major global health concern, particularly due to its aggressive nature and limited treatment options in advanced stages. Long noncoding RNA (lncRNA) TOB1‐AS1 has been proposed as a tumor suppressor, yet its regulatory mechanism in CC remains unclear.
Yang Wang   +4 more
wiley   +1 more source

Screening of Genomic Library of Soybean Cultivar Lumut by Using Peroxidase Gene from Arabidopsis thaliana as Probe

open access: yesJurnal Ilmu Dasar, 2010
Screening to genomic library of soybean cv. Lumut by using gene encoding for peroxidase (per) from A. thaliana as a probe has an objective isolate the whole gene of per from soybean.
Suharsono Suharsono   +2 more
doaj  

Hydrogen Peroxide-Based Fluorometric Assay for Real-Time Monitoring of SAM-Dependent Methyltransferases

open access: yesFrontiers in Bioengineering and Biotechnology, 2018
Methylated chemicals are widely used as key intermediates for the syntheses of pharmaceuticals, fragrances, flavors, biofuels and plastics. In nature, the process of methylation is commonly undertaken by a super-family of S-adenosyl methionine-dependent ...
M. Kalim Akhtar   +7 more
doaj   +1 more source

Modular Nucleic Acid Assembled p/MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells [PDF]

open access: yes, 2009
The human immune system consists of a large number of T cells capable of recognizing and responding to antigens derived from various sources. The development of peptide-major histocompatibility (p/MHC) tetrameric complexes has enabled the direct ...
Bailey, Ryan C.   +12 more
core   +2 more sources

Evaluation of two candidate molecules—TCTP and cecropin—on the establishment of Trypanosoma brucei gambiense into the gut of Glossina palpalis gambiensis

open access: yesInsect Science, EarlyView.
This study investigates the potential of enhancing the resistance of Glossina palpalis gambiensis to Trypanosoma brucei gambiense to mitigate the transmission of Human African Trypanosomiasis. We successfully cloned genes encoding proteins of interest in Sodalis strains, resulting in recombinant Sodalis (recSodalis) that were micro‐injected into the L3
François Sougal Ngambia Freitas   +9 more
wiley   +1 more source

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