Results 201 to 210 of about 225,565 (329)

中国人G6PD基因EcoRI酶切位点研究

Zhongshan Daxue xuebao. Yixue kexue ban, 1993
应用DNA Southern印迹杂交技术,以G6PD cDNA为探针,研究了16种限制酶的限制性片段长度多态,结果表明除EcoRⅠ外,其余15种限制酶均无多态改变,分析39例正常人与38例G6PD缺乏者G6PD基因ECO RⅠ酶切位点时,发现约20％的人出现7·0 kb的片段,1例G6PD患者出现6.0 kb片段,国外并无类似报道,并对这些片段来源及意义进行初步探讨。
doaj  

Enzyme- and DNAzyme-Driven Transient Assembly of DNA-Based Phase-Separated Coacervate Microdroplets. [PDF]

J Am Chem Soc
Qin Y, Sohn YS, Nechushtai R, Xia F, Huang F, Willner I.   +5 more
europepmc   +1 more source

Patterns and Processes of Genomic Evolution Inferred From the Ten Smallest Vertebrate Genomes

Advanced Science, Volume 12, Issue 38, October 13, 2025.
By integrating phylogenetic relationships derived from nuclear DNA with population genetic analyses across ten pufferfish species, the genetic differentiation mechanisms underpinning the radiative speciation of the most compact vertebrate genomes has elucidated.
Kaiqiang Liu, Qian Wang, Ning Wang, Lingfeng Meng, Shuo Li, Hong‐Yan Wang, Yuyan Liu, Qian Liu, Yangqing Zhang, Lucas B. Doretto, Mengqi Zhang, Yating Qin, Shanshan Pan, Shenglei Han, Weijing Li, Shanshan Liu, Fengtao Gao, Axel Meyer, Jussi Taipale, Guangyi Fan, Manfred Schartl, Jilin Zhang, Changwei Shao   +22 more
wiley   +1 more source

Correction: Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cells. [PDF]

Cell Mol Life Sci
Rose I, Greenwood M, Biggart M, Baumlin N, Tarran R, Hart SL, Baines DL.   +6 more
europepmc   +1 more source

Sequence variation of chloroplast DNA that involves EcoRI and ClaI restriction site polymorphisms in soybean.

, 1998
Akira Kanazawa, Azumi Tozuka, Yoshiya Shimamoto   +2 more
openalex   +2 more sources

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

Advanced Science, Volume 12, Issue 38, October 13, 2025.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang, Shengtao Cheng, Huiying Gu, Shan Zhong, Dapeng Zhang, Xin He, Weixian Chen, Haijun Deng, Jihua Ren, Peng Chen, Ming Tan, Hui Zhang, Fan Li, Zhenzhen Zhang, Yuan Hu, Juan Chen   +15 more
wiley   +1 more source

Multi-interface licensing of protein import into a phage nucleus. [PDF]

Nature
Kokontis C, Klein TA, Silas S, Bondy-Denomy J.   +3 more
europepmc   +1 more source

Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen, Yujie Zhu, Xi Yang, JiangBin Wu, Keyuan Chen, Wuqing Huang, Lu Fang, Qi Zhang, Jie Chen, Jianing Gao, Huanhuan Cao, Meifang Wu, Zhihuang Qiu, Yuling Zhang, Yue Shen, Qiuyu Huang, Zhiyong Lin, Lemin Zheng, Liangwan Chen   +18 more
wiley   +1 more source

Synthetic guide sequence to generate CRISPR-Cas9 entry strains in <i>C. elegans</i>. [PDF]

MicroPubl Biol
Lange KI.
europepmc   +1 more source

Sequence Analysis of the Leftward End of Simian Varicella Virus (EcoRI-I Fragment) Reveals the Presence of an 8-bp Repeat Flanking the Unique Long Segment and an 881-bp Open-Reading Frame That Is Absent in the Varicella Zoster Virus Genome

, 2000
Ravi Mahalingam, Tiffany White, Mary Wellish, Donald H. Gilden, Kenneth F. Soike, Wayne L. Gray   +5 more
openalex   +1 more source