Results 241 to 250 of about 225,565 (329)

Potential cytotoxicity of truncated slow skeletal muscle troponin T (ssTnT) in a loss of function TNNT1 myopathy mouse model

open access: yesThe FEBS Journal, Volume 292, Issue 20, Page 5525-5539, October 2025.
A loss of function TNNT1 myopathy mouse model with the nonsense mutation p.E180* showed potential cytotoxicity of the truncated slow troponin T fragment. The mRNA expression profile in the soleus muscle of Tnnt1‐p.E180* mice showed very different changes in comparison to that of Tnnt1‐knockout mice.
Han‐Zhong Feng   +2 more
wiley   +1 more source

Episomal and integrated hepatitis B transcriptome mapping uncovers heterogeneity with the potential for drug-resistance. [PDF]

open access: yesNat Commun
Harris JM   +10 more
europepmc   +1 more source

Biochemical characterization of phosphoenolpyruvate carboxykinases from multiple species of brown algae

open access: yesJournal of Phycology, Volume 61, Issue 5, Page 1321-1338, October 2025.
Abstract Phosphoenolpyruvate carboxykinase (PEPCK) is involved in the conversion of phosphoenolpyruvate (PEP) to oxaloacetate (OAA). In addition to playing a role in gluconeogenesis in various organisms, PEPCK also functions in the C4 cycle to concentrate CO2 for photosynthesis in some C4 plants.
Jian‐qiang Jin   +3 more
wiley   +1 more source

Genomic Insights Into Local Adaptation Across Heterogeneous Understory Habitats and Climate Change Vulnerability

open access: yesMolecular Ecology, Volume 34, Issue 19, October 2025.
ABSTRACT Understanding adaptive evolution and survival risks in understory herbs is crucial for the effective conservation of biodiversity. How environmental gradients shape species local adaptation patterns is not well understood, nor is how populations of understory herbs respond to a changing climate.
Nan Lin   +7 more
wiley   +1 more source

Role of the Multicopper Oxidase CueO in Copper Homeostasis Under Anaerobic Conditions in Enterobacteria

open access: yesMolecular Microbiology, Volume 124, Issue 4, Page 297-309, October 2025.
The periplasmic multicopper oxidase CueO oxidizes cuprous ions (Cu+) to cupric ions (Cu2+), a well‐known process typically coupled with oxygen reduction. In this study, we report unexpected anaerobic phenotypes associated with CueO, suggesting that it may use an alternative electron acceptor in the absence of oxygen.
Jérôme Becam   +4 more
wiley   +1 more source

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