Results 71 to 80 of about 223,024 (272)
Background: Facioscapulohumeral muscular dystrophy (FSHD), a common autosomal dominant muscular disorder, is caused by contraction of the D4Z4 repeats on 4q35.
Feng Lin +4 more
doaj +1 more source
Different fates of the chloroplast tufA gene following its transfer to the nucleus in green algae [PDF]
Previous work suggested that the tufA gene, encoding protein synthesis elongation factor Tu, was transferred from the chloroplast to the nucleus within the green algal lineage giving rise to land plants.
Baldauf, S.L. +2 more
core +4 more sources
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu +13 more
wiley +1 more source
Se exploró y caracterizó la diversidad fenotípica y genotípica de poblaciones del pasto punta blanca [Digitaria californica (Benth.) Henr.], en pastizales de Chihuahua. Se realizó análisis de componentes principales y conglomerados.
Carlos Raúl Morales Nieto +4 more
doaj
Analysis of DNA methylation in various swine tissues. [PDF]
DNA methylation is known to play an important role in regulating gene expression during biological development and tissue differentiation in eukaryotes. In this study, we used the fluorescence-labeled methylation-sensitive amplified polymorphism (F-MSAP)
Chun Yang +7 more
doaj +1 more source
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob +12 more
wiley +1 more source
Recombinant human epidermal growth factor (rh-EGF) has high value in therapies for h-EGF deficiency-related diseases. The expression of the h-EGF gene was designed by using the pET21b(+) vector and Escherichia coli BL21(DE3) as the expression host.
Achmad Rodiansyah +3 more
doaj +1 more source
Molecular cloning and characterization of a new member of the gap junction gene family, connexin-31 [PDF]
A new member of the connexin gene family has been identified and designated rat connexin-31 (Cx31) based on its predicted molecular mass of 30,960 daltons. Cx31 is 270 amino acids long and is coded for by a single copy gene.
Hoh, Jan H. +2 more
core
ER5, a tomato cDNA encoding an ethylene-responsive LEA-like protein: characterization and expression in response to drought, ABA and wounding [PDF]
We report the isolation by differential display of a novel tomato ethylene-responsive cDNA, designated ER5. RT-PCR analysis of ER5 expression revealed an early (15 min) and transient induction by ethylene in tomato fruit, leaves and roots.
Bouzayen, Mondher +6 more
core +2 more sources
Multi‐Targeting Non‐Specific Genome Engineering in Bacteria
In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun +7 more
wiley +1 more source

