Results 121 to 130 of about 12,803,103 (284)

Studying biodiversity-ecosystem function relationships in experimental microcosms among islands. [PDF]

Ecology, 2022
Teittinen A, Soininen J, Virta L.
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

A Habitat and a Parasite: Adult and Larval Parasitic Freshwater Mussels Impact Habitat Choice and Predator–Prey Interactions of a Host Fish and Its Prey

Ecology and Evolution
Parasitic freshwater mussels are endangered ecosystem engineers with an array of impacts on multiple trophic levels and life stages. While the impacts of adult mussels on separate trophic levels have been studied, few have directly tested how adult ...
Sebastian L. Rock, Anna M. Elmlund, P. Anders Nilsson, Johan Watz, Olle Calles, Martin Österling   +5 more
doaj   +1 more source

Impact of intercropping grass on the soil rhizosphere microbial community and soil ecosystem function in a walnut orchard. [PDF]

Front Microbiol, 2023
Wang C, Liang Q, Liu J, Zhou R, Lang X, Xu S, Li X, Gong A, Mu Y, Fang H, Yang KQ.   +10 more
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Omics-based ecosurveillance for the assessment of ecosystem function, health, and resilience. [PDF]

Emerg Top Life Sci, 2022
Beale DJ, Jones OAH, Bose U, Broadbent JA, Walsh TK, van de Kamp J, Bissett A.   +6 more
europepmc   +1 more source

Nutrient-induced acidification modulates soil biodiversity-function relationships

Nature Communications
Nutrient enrichment is a major global change component that often disrupts the relationship between aboveground biodiversity and ecosystem functions by promoting species dominance, altering trophic interactions, and reducing ecosystem stability. Emerging
Zhengkun Hu, M. Delgado‐Baquerizo, Nicolas Fanin, Xiaoyun Chen, Yan Zhou, Guozhen Du, Feng Hu, LIN-FENG Jiang, Shuijin Hu, Manqiang Liu   +9 more
semanticscholar   +1 more source

Heuristically Adaptive Diffusion‐Model Evolutionary Strategy

Advanced Science, EarlyView.
Building on the mathematical equivalence between diffusion models and evolutionary algorithms, researchers demonstrate unprecedented control over evolutionary optimization through conditional diffusion. By training diffusion models to associate parameters with specific traits, they can guide evolution toward solutions exhibiting desired behaviors ...
Benedikt Hartl, Yanbo Zhang, Hananel Hazan, Michael Levin   +3 more
wiley   +1 more source

Ecosystem Functioning [PDF]

Nature, 1968
openaire   +1 more source

Ecosystem Services Ecosystem Function and the Ecosystem Approach

, 2013
This project focused on mapping the delivery of three ecosystems services each in one case study area in Scotland and then identify how the Scottish policies such as woodland expansion biodiversity, conservation and food production affect the land use.
openaire   +1 more source