Results 121 to 130 of about 718,053 (303)

Safeguarding Important Areas in the U.S. Arctic Ocean [PDF]

, 2015
The U.S. Arctic Ocean supports unique species found nowhere else in the country and is home to indigenous Inupiat people who have thrived on its bounty for thousands of years.

core  

Marine biodiversity and ecosystem functioning

, 2009
Principali risultati del network europeo di eccellenza ...
Heip C, Hummel H, van Avesaath P, Appeltans W, Arvanitidis C, Aspden R, Austen M, Boero F, Bouma TJ, Boxshall G, Buchholz F, Crowe T, Delaney A, Deprez T, Emblow C, Feral JP, Gasol JM, Gooday A, Harder J, Ianora A, Kraberg A, Mackenzie B, Ojaveer H, Paterson D, Rumohr H, Schiedek D, Sokolowski A, Somerfield P, Sousa Pinto I, Vincx M, Węsławski JM, Nash R.   +31 more
openaire   +3 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Corrigendum: Rethinking the Ecosystem Functions of Dicranopteris, a Widespread Genus of Ferns

Frontiers in Plant Science, 2021
Long Yang, Yuhui Huang, Lucas Vieira Lima, Zhongyu Sun, Meijie Liu, Jun Wang, Nan Liu, Hai Ren   +7 more
doaj   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Eradication, Containment, Management and Restoration. A report to the European Commission Working Group 3 on Invasive Species Policy [PDF]

, 2011
• Working Group Invasive Species n. 3 • Task 3.1: Eradication, Containment, Management and Restoration o Objective o Scope o Definitions o Eradication o Containment o Mitigation o Coexistence and Acceptance o Restoration o The Role of EU and ...
Genovesi, Piero, McLennan, Staci, Newman, Jonathan, Robertson, Pete, Walton, Paul   +4 more
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Climate Change Threatens Micronutrient Density of European Winter Wheat

Advanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao, Jennifer Michel, Eline Lorer, Markus Weinmann, Jacques Le Gouis, Claire Léon, Sibille Perrochon, David Alvarez, Vincent Leemans, Iñaki Balanzategui Guijarro, Jordi Moya Laraño, Sara Sánchez Moreno, Symanczik Sarah, Waibel Matthias, Hervé Vanderschuren, Cécile Thonar, Pierre Delaplace, Dominique Van Der Straeten   +17 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Towards detailed predictions of coastal ecosystem function under climate change. [PDF]

PLoS Biol, 2023
Barneche DR, Morais RA.
europepmc   +1 more source

When is it Optimal to Exhaust a Resource in a Finite Time? [PDF]

Exhaustion of a natural resource stock may be a rational choice for an individual and/or a community, even if a sustainable use for the resource is feasible and the resource users are farsighted and well informed on the ecosystem.
Ken-Ichi Akao, Y. Hossein Farzin
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