Results 101 to 110 of about 16,523 (289)

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Including stakeholders’ perspectives on ecosystem services in multifunctionality assessments

Ecosystems and People, 2020
Multifunctional landscapes are used and shaped by a range of different stakeholders. The high number of diverging values, interests or demands in such landscapes can lead to conflicts that impact sustainability goals.
Lisanne Hölting, Franziska Komossa, Anna Filyushkina, Miene-Marie Gastinger, Peter H. Verburg, Michael Beckmann, Martin Volk, Anna F. Cord   +7 more
doaj   +1 more source

Environmental impact of organic agriculture in temperate regions [PDF]

, 2012
Can organic agriculture elaborate a scientifically based, resource-efficien and agroecological approach to low-input farm management? This review examines the literature from temperate regions, with a particular emphasison Canadian and USstudies that ...
Bhatta, G.D., Halberg, N., Lynch, D.H.
core   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Decadal warming-induced changes in abiotic factors and multitrophic diversity drive soil multifunctionality in an alpine meadow

Geoderma
Climate warming can be detrimental to biodiversity and ecosystem multifunctionality. Numerous studies have examined the effect of warming on ecosystem multifunctionality; however, little is known about how long-term warming affects ecosystem ...
Tianyang Zhou, Luming Ding, Xiaoyue Yin, Subinuer Wubuli, Jingying Feng, Changting Wang, Pengfei Wu, Allan Degen   +7 more
doaj   +1 more source

Bivariate Ordered Probit Analysis of Public Attitudes Toward Multifunctionality of Agriculture in the U.S. [PDF]

Agricultural and Food Policy,
Chang, Jae Bong, Moon, Wanki
core   +1 more source

Potential WTO Trade Reform: Multifunctionality Impacts for Ireland?. CEPS ENARPRI Working Papers No. 16, 7 June 2006 [PDF]

, 2006
The economic impact of trade policy reforms on various sectors of the economy receives more attention than the effects on the environment. This may be partly owing to the secondary importance attributed to environmental or multifunctionality issues when ...
Donnellan, Trevor, Hanrahan, Kevin.
core  

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Contrasting short- and long-term effects of warming and precipitation on ecosystem multifunctionality in a semiarid grassland

Ecological Indicators
Ecosystem multifunctionality (EMF) reflects an ecosystem's capacity to sustain multiple functions simultaneously and is highly sensitive to climate change.
Zhiqiang Wan, Lingman Dong, Rui Gu, Hasbagan Ganjurjav, Maowei Liang, Huiying Liu, Ze Zhang, Xiling Gu, Guozheng Hu, Qingzhu Gao, Xi Chun, Haijun Zhou, Enliang Guo, Fanhao Meng, Weiqing Zhang   +14 more
doaj   +1 more source