Results 91 to 100 of about 1,261,726 (302)

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

open access: yesAdvanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao   +5 more
wiley   +1 more source

A systematic review of terrestrial ecosystem resilience: Trends and adaptations over the past 50 years

open access: yesGeography and Sustainability
Resilience plays a crucial role in maintaining desirable ecosystem states and is a key objective of sustainable ecosystem management. This study synthesizes the concepts and measurement approaches of terrestrial ecosystem resilience and expounded on its ...
Tianjing Wu   +5 more
doaj   +1 more source

Groundwater Rise Sustains the World's Largest Alpine Water System Under Global Warming

open access: yesAdvanced Science, EarlyView.
Shallow groundwater depth (SGWD) across the non‐permafrost plains of the Qinghai–Xizang Plateau decreased at averagely 0.02 m year−1, adding 31.44 Gt of freshwater storage from 2000 to 2020 and sustaining ∼53 500 km2 of alpine ecosystems. A vadose‐zone capacity of 426.6 Gt reveals these aquifers as promising reservoirs, highlighting groundwater's ...
Jianqing Du   +15 more
wiley   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Building farm resilience [PDF]

open access: yes, 2003
Organic farming emerged as a social movement promoting social justice and ecological sustainability within agriculture. In recent years, the organic sector has grown substantially throughout Europe.
Milestad, Rebecka
core   +1 more source

Spatiotemporal changes of ecosystem resilience and its prediction under different development scenarios in Ji county, Shanxi province

open access: yes中国水土保持科学
ObjectiveEcosystem resilience reflects the capacity of an ecosystem to resist, adapt to, and recover from disturbances, and is a key indicator for assessing ecosystem stability.
Zehui LIU   +5 more
doaj   +1 more source

Linking Biodiversity, Ecosystem Functioning and Services, and Ecological Resilience

open access: yes, 2015
Final ecosystem services (i.e. services that directly benefit humanity) depend fundamentally upon the various processes, regulated by organisms, which underpin ecosystem functioning and maintain ecosystem structures.
Sponseller, Ryan A.,   +9 more
core   +1 more source

Boundary object or bridging concept? A citation network analysis of resilience [PDF]

open access: yes, 2015
Many recent studies observe the increasing importance, influence, and analysis of resilience as a concept to understand the capacity of a system or individual to respond to change. The term has achieved prominence in diverse scientific fields, as well as
Brown, Katriana   +5 more
core   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

open access: yesAdvanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan   +5 more
wiley   +1 more source

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