Results 71 to 80 of about 665,463 (269)
A Policy Maker’s Guide to Designing Payments for Ecosystem Services [PDF]
, 2009 Over the past five years, there has been increasing interest around the globe in payment schemes for the provision of ecosystem services, such as water purification, carbon sequestration, flood control, etc.
James E. Salzman +31 more
core +3 more sources
Ecology and EvolutionSemi‐natural grasslands and their biodiversity decline rapidly, although they are key elements of agricultural landscapes. Therefore, there is a need for the re‐establishment of semi‐natural grasslands in intensively managed farmlands (e.g., via sowing ...
Flóra Vajna +6 more
doaj +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions
Advanced Science, EarlyView.This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao +4 more
wiley +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Advanced Science, EarlyView.A Lattice Genome framework links geometric and process “genes” to lattice “phenotypes” via correction‐calibrated high‐throughput simulations and a growing performance database. Genome‐driven retrieval and recombination of unit cells enables component‐level, regionally tailored multi‐objective design: stress fields are programmed under constant relative
Haoyuan Deng +8 more
wiley +1 more source
Valuing ecosystem services: A new paradigm shift [PDF]
, 2006 The ways in which economists value natural resources has been, and continues to be, a constantly evolving process. At first, only transactions that took place in the marketplace were considered.
Kaval, Pamela
core +1 more source
Advanced Science, EarlyView.Schematic diagram of our study showing that highly expressed POU2F1 in colorectal cancer (CRC) can directly accelerate the cytosolic lactate export to decrease PPP1R11 lactylation at K59, thereby attenuating the E3 ligase enzyme activity and protein stability of PPP1R11, which inhibits the ubiquitination of MDR2 at K413 and K538 but increases the ...
Longzheng Xia +8 more
wiley +1 more source
Ecosystem Services in Decision Making: Time to Deliver [PDF]
, 2009 Over the past decade, efforts to value and protect ecosystem services have been promoted by many as the last, best hope for making conservation mainstream – attractive and commonplace worldwide.
Daily, Gretchen C. +8 more
core +2 more sources
Cahiers AgriculturesThis article reports on pesticide use in rice production by 210 farmers across seven provinces in Cambodia along a gradient of intensification defined by the number of rice crops per year.
Ngang Linna +8 more
doaj +1 more source