Results 101 to 110 of about 343,772 (315)
Advanced Science, EarlyView.The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Surviving Fetus from a Full Term Abdominal Pregnancy
International Medical Case Reports Journal, 2023 Tesfaye Kebede Legesse,1 Birhanu Abera Ayana,2 Semira Abrar Issa1 1Department of Radiology, Addis Ababa University, College of Health Science, Addis Ababa, Ethiopia; 2Department of Obstetrics and Gynecology, Addis Ababa University, College of Health ...
Legesse TK, Ayana BA, Issa SA
doaj
Dentigerous cyst with an ectopically erupted supernumerary tooth in maxillary sinus
SRM Journal of Research in Dental Sciences, 2012 An ectopically erupted tooth in the maxillary sinus presents itself as a confounding problem, which may lead tomaxillary sinusitis. A case of a cyst associated with an ectopic supernumerary tooth in the left maxillary sinus cavity is presented, which is ...
Ramesh Srinivasan +1 more
doaj +1 more source
The prevalence of impacted permanent maxillary canines in Maltese school children : a pilot study [PDF]
, 1995 The aetiology of ectopic canines is not clear. A number of causes have been put forward such as the long path of eruption of the maxillary canine, lack of guidance by the lateral incisor root, narrow arches, cystic enlargement of the dental follicle ...
Camilleri, Simon
core
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Understanding Ectopic Kidneys: Insights from a Single-Center Study [PDF]
Introduction: The failure of the normal ascent of the kidney can result in ectopic kidneys (EK) and fusion anomalies. EKs are often accompanied by urological and extrarenal abnormalities.
Adem Yasin Köksoy +2 more
core +1 more source
, 2011 Ectopic pregnancy is the second major cause of maternal mortality in the United States and a leading cause of maternal morbidity and mortality in the world.
core +1 more source
Advanced Science, EarlyView.In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu +18 more
wiley +1 more source
Several early interventions for ectopic maxillary canines.
Journal of Oral Research, 2012 Maxillary canine impactation is often encountered in orthodontic clinical practice and the aetiology is associated to genetic factors as well as local space factors.
Carlos Astorga +3 more
doaj +1 more source