Results 171 to 180 of about 9,800 (223)

Ectopic ACTH syndrome

The Journal of Steroid Biochemistry and Molecular Biology, 1995
Ectopic ACTH syndrome represents a cancer-induced amplification of a property [proopiomelanocortin (POMC) peptides production] normally present in the cells from which the cancer originated but with aberrant posttranslational processing of POMC resulting in a greatly elevated secretion of ACTH precursors.
B L, Wajchenberg, B, Mendonça, B, Liberman, M, Adelaide, A, Pereira, M A, Kirschner   +5 more
openaire   +2 more sources

ACTH precursors characterize the ectopic ACTH syndrome

Clinical Endocrinology, 1994
SummaryOBJECTIVE ACTH is secreted by the pituitary following processing of larger molecular weight precursors, proopiomelanocortin and pro‐ACTH. Ectopic ACTH syndrome refers to the secretion of ACTH by non‐pituitary tumours, but the predominant circulating form of proopiomelano‐cortin‐related peptides remains unclear.PATIENTS Fifteen patients with ...
Stewart, P. M., Gibson, S., Crosby, S. R., Penn, R., Holder, R., Ferry, D., Thatcher, N., Phillips, P., London, D. R., White, A.   +9 more
openaire   +3 more sources

Occult ectopic ACTH syndrome

The Lancet, 2001
A 38-year-old male was diagnosed with Cushing's syndrome. Biochemical tests showed hypokalaemia and hypercortisolaemia, with failure of suppression following high dose dexamethasone, suggesting an ectopic or adrenal source. Adrenocorticotrophic hormone levels were >100 IU/L (normal 3–14 IU/L).
DJR Cuthbertson, S Vinjamuri, D Bowen-Jones   +2 more
openaire   +1 more source