Results 31 to 40 of about 1,185 (183)

Targeted Alkaline Phosphatase Therapy Enhances Alveolar Bone Healing in X‐Linked Hypophosphatemia in Mice

Journal of Periodontal Research, EarlyView.
Effects of exogenous tissue‐nonspecific alkaline phosphatase (TNAP) were analyzed in the Hyp mouse model of X‐linked hypophosphatemia (XLH). Maxillary first molars were extracted from wild‐type (WT) and Hyp mice at 6 weeks, and collagen gel ± TNAP was placed in sockets. In one group of Hyp mice, submucosal injections of TNAP or saline were delivered at
Aonjittra Phanrungsuwan, Bella Donnelly, José Luis Millán, Brian L. Foster   +3 more
wiley   +1 more source

Rationales for the Bernese approaches in acetabular surgery [PDF]

, 2018
Purpose: To present two new approaches to acetabular surgery that were established in Berne, and which aim at enhanced visualization and anatomical reconstruction of acetabular fractures.
Bastian, J., Ecker, T., Keel, M., Siebenrock, K.-A   +3 more
core  

Bone Grafts: Everything You Need to Know

Journal of Periodontal Research, EarlyView.
This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen, Javier Sanz, Giuseppe Perale, Augustine Mark Saiz, Mario Romandini, Maryam Rahmati   +5 more
wiley   +1 more source

A Network‐Based Approach to Understanding Key Signaling Pathways in Intervertebral Disc Biology

JOR SPINE, Volume 9, Issue 2, June 2026.
A literature‐based signaling network capturing the most relevant pathways in human nucleus pulposus cells was first constructed from curated biological evidence. The network was then translated into a system of ordinary differential equations to derive steady‐state solutions and define median baseline activity levels.
Sofia Tseranidou, Zerihun G. Workineh, Maria Segarra‐Queralt, Francis Kiptengwer Chemorion, Paola Bermudez‐Lekerika, Exarchos Kanelis, Katherine B. Crump, Benjamin Gantenbein, Leonidas G. Alexopoulos, Christine L. Le Maitre, Janet Piñero, Jérôme Noailly   +11 more
wiley   +1 more source

The Role of Surgical Hip Dislocation in the Treatment of Acetabular and Femoral Head Fractures [PDF]

, 2018
: Background and Purpose: : Surgical hip dislocation by trochanteric flip osteotomy facilitates access to acetabular and femoral head fractures. Furthermore, it allows evaluation of cartilage damage and vascularity of the femoral head.
Eid, Karim, Ertel, Wolfgang, Isler, Balz, Keel, Marius, Trentz, Otmar   +4 more
core  

Congenital imprinting disorders: EUCID.net - a network to decipher their aetiology and to improve the diagnostic and clinical care. [PDF]

, 2015
Imprinting disorders (IDs) are a group of eight rare but probably underdiagnosed congenital diseases affecting growth, development and metabolism. They are caused by similar molecular changes affecting regulation, dosage or the genomic sequence of ...
Eggermann, Thomas, Grønskov, Karin, Linglart, Agnès, Mackay, Deborah, Maher, Eamonn R, Monk, David, Netchine, Irène, Riccio, Andrea, Temple, I Karen, Tümer, Zeynep   +9 more
core   +5 more sources

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

Advanced Science, Volume 13, Issue 14, 9 March 2026.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong, Hang Zhou, Chenyang Ye, Lei Chu, Lin Wang, Yingjun Wang   +5 more
wiley   +1 more source

Calcificaciones heterotópicas en cirugía protésica de cadera: Prótesis bicénctricas vs híbridas [PDF]

, 1999
Realizamos el seguimiento clínico y radiológico de 202 pacientes a los que se implantó una Prótesis Total de Cadera cementada (PTC). Analizamos la presencia de calcificaciones heterotópicas (CH) y su graduación, estudiando separadamente prótesis híbridas
Galdo Pérez, M., Montero Furelos, Luis Angel, Sánchez Mozo, A., Yubero Pascual, J.   +3 more
core  

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

Developmental Dynamics, Volume 255, Issue 3, Page 228-245, March 2026.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe   +6 more
wiley   +1 more source

Mechanosensitive Ion Channel PIEZO1 Suppresses BMP2‐Induced Ossification of the Annulus Fibrosus Cells

JOR SPINE, Volume 9, Issue 1, March 2026.
This study aimed to elucidate the function of PIEZO1in AF cells under mechanical stimulation. Low‐magnitude cyclictensile strain (CTS, 2%) suppressed osteogenic marker expression. Pharmacological activation of PIEZO1 using Yoda1 mimics the effects oflow‐strain CTS.
Hisakazu Shitozawa, Ryo Nakamichi, Aki Yoshida, Masataka Ueda, Taichi Saito, Koji Uotani, Yoshiaki Oda, Ryo Takatori, Kazutaka Yamashita, Toshifumi Ozaki   +9 more
wiley   +1 more source