Results 81 to 90 of about 19,410 (290)

Jože Vesenjak (1920–1991), an Apostle of Christian Unity and a Devoted Pastoral Worker

open access: yesEdinost in Dialog, 2021
We present Jože Vesenjak (August 27, 1920, Moškanjci, Parish of St. Marjeta niže Ptuja – June 23, 1991, Maribor), priest, chaplain, pastor, spiritual theologian and one of the pioneers of the ecumenical movement in Slovenia.
Vinko Škafar
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Exploring the relationship between theology and learning through the lens of disruption

open access: yesJournal of Learning Development in Higher Education
As in many other contexts, for theological education practitioners, successful teaching and learning outcomes not only include students’ clear comprehension of curriculum content but also the cultivation of skills to contextualise learning in multiple ...
Jen Smith
doaj   +1 more source

The ecumenical dialogue: issues and answers by John Paul II

open access: yesУкраїнське Pелігієзнавство, 2016
The article of Sergiy Prysukhin «The ecumenical dialogue: issues and answers by John Paul II (on the occasion of 15th anniversary of Pastoral Visit to the Ukraine, 2001)» is devoted to theology works of John Paul II in relation to the analysis of ...
Sergiy Prysukhin
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

The development of the understanding of ministry in the Australian church union negotiations 1957-1971 [PDF]

open access: yes, 2013
Barely three years after the formation of the Uniting Church in Australia, the Assembly Standing Committee urged the Commission on Doctrine to 'give first priority to matters relating to ministry'.
Dutney, Andrew Fergus
core   +2 more sources

Johan Heyns as ekumeniese figuur

open access: yesVerbum et Ecclesia, 1994
Johan Heyns as ecumenical figure The role that Heyns played in ecumenical developments within the Dutch Reformed Church since 1986 is described. He played a leading role in breaking the ecumenical isolation of the Church.
D. Crafford
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

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