Results 71 to 80 of about 77,571 (314)
Daring to Share: Multi-Denominational Congregations in the United States and Canada [PDF]
, 2018 Daring to Share: Multi-Denominational Congregations in the United States and Canada, by Sandra Beardsall, Mitzi J Budde, and William P McDonald.
Salmon, Ann J.
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Living in to its Name and Living up to its Legacy: The public practical theology of KAIROS [PDF]
, 2015 KAIROS Canada looks hopefully towards the emerging challenges of continuing public practical theology in a pluralistic, post-apology time and ...
Henry, Jennifer
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BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
The Mind: Embodied, Embedded, but not Extended [PDF]
, 1998 This commentry focuses on the one major ecumenical theme propounded in Andy Clark's Being There that I find difficult to accept; this is Clarks advocacy, especially in the third and final part of the book, of the extended nature of the embedded ...
O'Brien, Gerard
core
Book Review: Indian Theology in Dialogue [PDF]
, 1988 A review of Klaus Klostermaier\u27s Indian Theology in ...
Neufeldt, Ronald
core +2 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
‘Ought’-contextualism beyond the parochial [PDF]
, 2019 Despite increasing prominence, ‘ought’-contextualism is regarded with suspicion by most metaethicists. As I’ll argue, however, contextualism is a very weak claim, that every metaethicist can sign up to.
Worsnip, Alex
core
Where Do We Go From Here? [PDF]
, 2017 (excerpt) Truth is, though, we need wise and discerning counsel in order learn how to be liturgists for our assemblies. Liturgists, whether worship leaders or planners, presiding or assisting, spoken or musical, all need a coherent sense of their ...
Brugh, Lorraine
core +2 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source