Results 51 to 60 of about 19,757 (178)

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Legitimacy challenges in emerging electric commercial vehicle (ECV) ecosystem [PDF]

The electrification of transport is widely recognized as a promising solution with significant potential to decrease carbon dioxide emissions. However, despite ongoing technological advancements, businesses have been reluctant to fully adopt electric ...
Ahokangas, Petri, Dehkordi, Rashid, Evers, Natasha, Sorvisto, Mika   +3 more
core   +1 more source

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source

FDG PET/CT imaging and circulating biomarkers of inflammation in desmoplakin cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1485-1489, April 2025.
Abstract Aims Inflammation has been implicated in the pathogenesis of desmoplakin (DSP) cardiomyopathy, and retrospective studies have described abnormal myocardial fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) findings in symptomatic patients eventually diagnosed with DSP cardiomyopathy.
Sanjay Divakaran, Vinay Randhawa, Usman A. Tahir, Matthew Robertson, Anam A. Waheed, Anna Perillo, Leanne Barrett, Ron Blankstein, Mark W. Feinberg, Marcelo F. Di Carli, Neal K. Lakdawala   +10 more
wiley   +1 more source

Development and Validation of Imaging‐Free Myocardial Fibrosis Prediction Models, Association with Outcomes, and Sample Size Estimation for Phase 3 Trials

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Phase 3 trials testing whether pharmacologic interventions targeting myocardial fibrosis improve outcomes require myocardial fibrosis measurement that does not rely on tomographic imaging with intravenous contrast.
Nicholas Black, Joshua Bradley, Gavin Lewis, Jakub Lagan, Christopher Orsborne, Fardad Soltani, John P. Farrant, Theresa McDonagh, Matthias Schmitt, João L. Cavalcante, Martin Ugander, Javed Butler, Mark C. Petrie, Christopher A. Miller, Erik B. Schelbert   +14 more
doaj   +1 more source

Extracellular volume and left ventricular hypertrophy by cardiac magnetic resonance are independent predictors of cardiovascular outcome in obesity

Scientific Reports, 2022
This retrospective cohort study investigated for association between increased extracellular volume (ECV) and left ventricular hypertrophy (LVH) by cardiac magnetic resonance (CMR) and cardiovascular composite outcomes in obesity.
Panuwat Lertlaksameewilai, Thammarak Songsangjinda, Yodying Kaolawanich, Ahthit Yindeengam, Rungroj Krittayaphong   +4 more
doaj   +1 more source

Knowledge, attitudes, and practices of obstetrics residents towards cesarean delivery–sparing procedures

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives Obstetrics and gynecology (ObGyn) trainees will impact future practice patterns and their cesarean rates. The knowledge, attitudes, and practices (KAP) of ObGyn residents have not been extensively studied. We aimed to assess KAP towards mode of delivery and cesarean‐sparing procedures among ObGyn trainees.
Lina Roa, Kaitlyn E. James, Hossam Fahem Abdel‐Rahim, Maclean Abonie, Kwame Adu‐Bonsaffoh, Onesmus Byamukama, Samantha DeAndrade, Rossana Pulcineli Vieira Francisco, Henry Mark Lugobe, Lars Ladfors, Saknan Manotaya, Jania A. Ramos, Sarrah Shahawy, Kasemsri Srisupundit, Emma Svensson, Adeline A. Boatin   +15 more
wiley   +1 more source

Discrete components of stress impact trajectories of childhood irritability but not adolescent mental health outcomes

JCPP Advances, EarlyView.
Thick red line indicates positive mixture effect of stressors predicting high irritability class. Maternal demoralization, material hardship, maternal perceived stress, and intimate partner violence contributed to the mixture effect (thick borders on boxes).
Mariah DeSerisy, Huiyu Yang, Jacob W. Cohen, David Pagliaccio, Julie B. Herbstman, Bradley S. Peterson, Frederica P. Perera, Virginia Rauh, Amy E. Margolis   +8 more
wiley   +1 more source

Characteristics of E-cigarette or vape (ECV) users and patterns of use: Malaysia chapter [PDF]

, 2017
The use of e-cigarette or vape (ECV) is increasing rapidly internationally and also nationally. However, the characteristics of ECV users and patterns of its use in Malaysia are still scarce. Objectives: To explore and assess characteristics and patterns
Shafie, Asrul Akmal, Draman, Samsul, Robinson, Fredie, Yasin, Siti Munira, Ab Rahman, Norny Syafinaz, Ab Rahman, Jamalludin, Nik Mohamed, Mohamad Haniki, Kartiwi, Mira, Anselm, Su Ting, Tee, Guat Hiong, Daud, Aziah   +10 more
core  

Extracellular Volume Fraction Analysis on Cardiac Computed Tomography Is Useful for Predicting the Prognosis of Hypertrophic Cardiomyopathy

Journal of Cardiovascular Development and Disease
Extracellular volume fraction (ECV) analysis on computed tomography (CT) is now available. The purpose of this study was to assess the usefulness of CT-derived ECV analysis for predicting outcomes in patients with hypertrophic cardiomyopathy (HCM).
Shuhei Aoki, Hiroyuki Takaoka, Tomonori Kanaeda, Kazunari Asada, Joji Ota, Yoshitada Noguchi, Moe Matsumoto, Yusei Nishikawa, Katsuya Suzuki, Satomi Yashima, Makiko Kinoshita, Noriko Suzuki-Eguchi, Haruka Sasaki, Kohei Takahashi, Yoshihito Ozawa, Yosuke Inaba, Yoshio Kobayashi   +16 more
doaj   +1 more source