Hyperkeratotic hand eczema: Eczema or not? [PDF]
AbstractBackgroundHyperkeratotic hand eczema (HHE) is a typical clinical hand eczema subtype with a largely unknown pathophysiology.ObjectiveTo investigate histopathology, expression of keratins (K), epidermal barrier proteins, and adhesion molecules in HHE.MethodsPalmar skin biopsies (lesional and perilesional) were obtained from seven HHE patients ...
Klaziena Politiek+8 more
openaire +3 more sources
Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial. [PDF]
BACKGROUND: Skin barrier dysfunction precedes eczema development. We tested whether daily use of emollient in the first year could prevent eczema in high-risk children. METHODS: We did a multicentre, pragmatic, parallel-group, randomised controlled trial
BEEP study team+21 more
core +7 more sources
Economic evidence for the prevention and treatment of atopic eczema: a protocol for a systematic review [PDF]
Background: Eczema, synonymous with atopic eczema or atopic dermatitis, is a chronic skin disease that has a similar impact on health-related quality of life as other chronic diseases.
AS Paller+18 more
core +1 more source
Measurement properties of quality of life measurement instruments for infants, children and adolescents with eczema: protocol for a systematic review [PDF]
Background: Eczema is a common chronic or chronically relapsing skin disease that has a substantial impact on quality of life (QoL). By means of a consensus-based process, the Harmonising Outcome Measures in Eczema (HOME) initiative has identified QoL as
AD Furlan+23 more
core +2 more sources
An algorithm for diagnosing IgE-mediated food allergy in study participants who do not undergo food challenge. [PDF]
BACKGROUND: Food allergy diagnosis in clinical studies can be challenging. Oral food challenges (OFC) are time-consuming, carry some risk and may, therefore, not be acceptable to all study participants.
Batt, R+9 more
core +2 more sources
‘It's like the bad guy in a movie who just doesn't die’ : a qualitative exploration of young people's adaptation to eczema and implications for self‐care [PDF]
Background Eczema is a common childhood inflammatory skin condition, affecting more than one in five children. A popular perception is that children ‘outgrow eczema’, although epidemiological studies have shown that, for many, eczema follows a lifelong ...
Ghio, D+6 more
core +3 more sources
Do early-life exposures explain why more advantaged children get eczema? Findings from the U.K. Millennium Cohort Study [PDF]
Background: Atopic dermatitis (eczema) in childhood is socially patterned, with higher incidence in more advantaged populations. However, it is unclear what factors explain the social differences.
Hope, S.+4 more
core +1 more source