Results 101 to 110 of about 157,660 (290)
Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis
Med Research, EarlyView.The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang +7 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Rocatinlimab (AMG 451/KHK4083) is a potential T‐cell rebalancing therapy that inhibits and reduces the number of pathogenic T cells by targeting the OX40 receptor; it is associated with a progressive and sustained response for patients with moderate‐to‐severe atopic dermatitis (AD).
Hiroki Okada +8 more
wiley +1 more source
Eczema phenotypes and IgE component sensitization in adolescents: A population-based birth cohort
Allergology International, 2023 Background: Eczema patients are commonly immunoglobulin (Ig)E polysensitized. Although atopic dermatitis (AD) phenotypes have been recognized, IgE sensitization patterns based on AD phenotypes have not been well illustrated.
Tomoyuki Kiguchi +4 more
doaj
Effectiveness and Safety of Advanced Dual‐Targeted Therapy in Refractory Perianal Crohn's Disease
United European Gastroenterology Journal, EarlyView.ABSTRACT Introduction Perianal Crohn's disease (CD) remains challenging to treat despite the increasing number of advanced therapies. Advanced dual‐targeted therapy has emerged as a new treatment option in CD, but no data are available for perianal CD. The aim of this study was to evaluate the effectiveness and safety of advanced dual‐targeted therapy ...
Nadia Fathallah +9 more
wiley +1 more source
Fish Consumption, Fish Atopy and Related Heavy Metals in Childhood Eczema
Iranian Journal of Allergy, Asthma and Immunology, 2012 Due to increasing worldwide water pollution, fish might be a source of excessive zinc, mercury, arsenic or manganese intake. The aim of this study was to evaluate if fish atopy/sensitization and fish consumption behavior are associated with ...
Kam Lun Hon +4 more
doaj
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu +7 more
wiley +1 more source
Correlation between dietary calcium intake and eczema in American adult population
Scientific ReportsEczema is a common chronic skin condition. Previous studies indicated the dietary factors, such as calcium intake, might influence the onset and progression of eczema in the population of gravidas and infants.
Qianjie Wu +3 more
doaj +1 more source