Results 131 to 140 of about 204,314 (304)

Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma   +7 more
wiley   +1 more source

Validation of the Recap of Atopic Eczema (RECAP) Measurement Instrument for Eczema Control in Adult Patients in an Asian Clinical Setting

open access: yesActa Dermato-Venereologica
Recap of atopic eczema (RECAP) is a self-reported 7-item questionnaire recommended by the Harmonising Outcome Measures in Eczema initiative to measure eczema control.
Yik Weng Yew   +4 more
doaj   +1 more source

Measuring Peripheral Tissue DHA Turnover Using a Novel 13C Enrichment Technique

open access: yesLipids, EarlyView.
ABSTRACT Recently, through the use of compound‐specific isotope analysis (CSIA), our lab validated the utility of 13C enrichment (δ13C) of docosahexaenoic acid (DHA) by using a very high δ13C in a diet switch study by measuring brain, liver, and plasma DHA turnover and half‐lives via high‐precision gas chromatography combustion isotope ratio mass ...
Brinley J. Klievik   +3 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Successful treatment of severe and recurrent hand eczema with infection in human immunodeficiency virus patients: A case report

open access: yesSAGE Open Medical Case Reports
Hand eczema is a common allergic disease characterized by a chronic relapsing course with a 15% lifetime prevalence. Human immunodeficiency virus-infected individuals have a higher risk of Staphylococcus aureus infection which is associated with the ...
Dongmei Chen, Wei Liu, Yanxi Li
doaj   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca   +2 more
wiley   +1 more source

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