Background Psoriasis and atopic eczema are common inflammatory skin diseases. Existing research has identified increased risks of common mental disorders (anxiety, depression) in people with eczema and psoriasis; however, explanations for the ...
Alasdair D. Henderson +9 more
doaj +1 more source
Report from the third international consensus meeting to harmonise core outcome measures for atopic eczema/dermatitis clinical trials (HOME). [PDF]
This report provides a summary of the third meeting of the Harmonising Outcome Measures for Eczema (HOME) initiative held in San Diego, CA, U.S.A., 6-7 April 2013 (HOME III).
Admani, S +43 more
core +1 more source
Filaggrin loss-of-function mutations and atopic dermatitis as risk factors for hand eczema in apprentice nurses:part II of a prospective cohort study [PDF]
BACKGROUND/OBJECTIVES: Environmental exposure and personal susceptibility both contribute to the development of hand eczema. In this study, we investigated the effect of loss-of-function mutations in the filaggrin gene (FLG), atopic dermatitis and wet ...
Bakker, Jan G. +8 more
core +2 more sources
Eczema, one of the most prevalent inflammatory skin diseases among children, is potentially influenced by genetic, environmental and social factors. However, few studies have investigated the effect of residential environment and lifestyle on childhood ...
Yanlin Liu +7 more
doaj +1 more source
Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients [PDF]
Introduction: Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood.
Behrendt, Heidrun +7 more
core +2 more sources
Assessing the severity of eczema in clinical research requires face-to-face skin examination by trained staff. Such approaches are resource-intensive for participants and staff, challenging during pandemics, and prone to inter- and intra-observer ...
Rahman Attar +9 more
doaj +1 more source
Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice Research Database (GPRD). [PDF]
Background The General Practice Research Database (GPRD) and Doctor's Independent Network Database (DIN), are large electronic primary care databases compiled in the UK during the 1990s.
David P Strachan +15 more
core +3 more sources
Presenteeism in a Dutch hand eczema population-a cross-sectional survey [PDF]
Background: Presenteeism (attending work despite complaints and ill health, which should prompt rest and absence) has been overlooked in the field of hand eczema.
Bültmann, Ute +3 more
core +3 more sources
Early-Life Skin Microbial Biomarkers for Eczema Phenotypes in Chinese Toddlers
Eczema is a common inflammatory skin disorder during infancy. Evidence has shown that skin-microbiome fluctuations may precede eczema development, but their predictive value for eczema phenotypes remains unknown.
Yehao Chen +11 more
doaj +1 more source
Visualisation of tissue kallikrein, kininogen and kinin receptors in human skin following trauma and in dermal diseases [PDF]
During dermal injury and inflammation the serine proteases kallikreins cleave endogenous, multifunctional substrates (kininogens) to form bradykinin and kallidin.
Bhoola, Kanti D. +7 more
core +1 more source

