Results 31 to 40 of about 204,314 (304)

EDA Complex‐Driven Desaturation of Heterocyclic Carbonyl Compounds Enabled by HFIP

Angewandte Chemie, EarlyView.
In this work, we report a novel light‐mediated desaturation strategy enabled by electron donor–acceptor complex formation. DFT and mechanistic studies reveal that the reaction proceeds via single‐electron transfer, hydrogen atom transfer, and base‐mediated deprotonation sequentially with pyridinium salt serving dually as oxidant and base, and ...
Rakesh Maiti, Robin Cauwenbergh, Aritra Nath, Ana B. R. Guimarães, Yuman Qin, Feliu Maseras, Shoubhik Das   +6 more
wiley   +2 more sources

Disidrose: aspectos clínicos, etiopatogênicos e terapêuticos Dyshidrotic eczema: clinical, etiopathogenic and therapeutic aspects

Anais Brasileiros de Dermatologia, 2008
A disidrose e as erupções disidrosiformes são dermatoses vesiculosas muito freqüentes e de localização palmar e/ou plantar, de difícil tratamento e de evolução recidivante. Sua cura definitiva depende da descoberta do agente etiológico e da possibilidade
Lorivaldo Minelli, Ryssia Alvarez Florião, Manoel Sternick, Airton dos Santos Gon   +3 more
doaj   +1 more source

Hydrolysed formula and risk of allergic or autoimmune disease: a systematic review and meta-analysis [PDF]

, 2016
Objective To determine whether feeding infants with hydrolysed formula reduces their risk of allergic or autoimmune disease. Design Systematic review and meta-analysis, as part of a series of systematic reviews commissioned by the UK Food Standards ...
Boyle, RJ, Garcia-Larsen, V, Ierodiakonou, D   +2 more
core   +1 more source

Challenges in interpreting allergen microarrays in relation to clinical symptoms: a machine learning approach. [PDF]

, 2013
Identifying different patterns of allergens and understanding their predictive ability in relation to asthma and other allergic diseases is crucial for the design of personalized diagnostic tools.Allergen-IgE screening using ImmunoCAP ISAC(®) assay was ...
Altmann, Beeh, Bolstad, Breiman, Burrows, Crapo, Custovic, Fayyad, Friedman, Gent, Huber, Knop, Marinho, Melioli, Millán, Murthy, Patelis, Semic-Jusufagic, Simpson, Simpson, Sordillo, Taylor, Wang   +22 more
core   +1 more source

Comparative analysis of epidemiological data as well as quality of life in patients having hand eczema vis-à-vis foot eczema

Indian Dermatology Online Journal, 2019
Context: Eczema of hand or foot though not life-threatening, not only impacts daily activities and work productivity adversely, but also impairs interpersonal relationships. Materials and Methods: Cross-sectional study of 100 outpatients of hand and foot
Prachi V Agrawal, Ajay Kumar, Yugal K Sharma, Mahindra Deora, Rahul H Ranpariya   +4 more
doaj   +1 more source

Evaluating Access to Prescription Medications in the Atopic Dermatitis Patient Population in the USA

Dermatology and Therapy
Introduction Despite advances in atopic dermatitis (AD) treatments, many patients face challenges obtaining medications. This study aimed to determine the frequency and causes of insurance coverage delays and denials for AD prescriptions and characterize
Allison R. Loiselle, Raj Chovatiya, Isabelle J. Thibau, Jessica K. Johnson, Michele Guadalupe, Wendy Smith Begolka   +5 more
doaj   +1 more source

Assessing the Burden of Atopic Dermatitis in Portugal through Patient-Centered Experiences

Acta Médica Portuguesa
Introduction: Adult patients and caregivers of children with atopic dermatitis experience high physical, mental, and financial burden in Portugal. We outline the experience of atopic dermatitis management and how the current medical care model impacts ...
Michelle Tu, Freya Moxham, Alan Schwartz, Joana Camilo, Korey Capozza   +4 more
doaj   +1 more source

Early-onset eczema is associated with increased milk sensitization and risk of rhinitis and asthma in early childhood

Journal of Microbiology, Immunology and Infection, 2020
Background: Atopic eczema and food allergy most commonly occur in the early childhood. However, the relationships between eczema onset and their relevance to the occurrence of atopic diseases relating to allergen sensitization remain unclear. Methods: We
Chih-Yung Chiu, Chia-Hsuan Yang, Kuan-Wen Su, Ming-Han Tsai, Man-Chin Hua, Sui-Ling Liao, Shen-Hao Lai, Li-Chen Chen, Kuo-Wei Yeh, Jing-Long Huang   +9 more
doaj   +1 more source

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

Advanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa, Ana B. Carneiro, Filipa Lebre, João Meneses, Alar Ainla, Cacilda Moura, Ernesto Alfaro‐Moreno, Ana R. Ribeiro   +7 more
wiley   +1 more source

A Multicenter Validation of a Fully Automated Chemiluminescence Immunoassay for Plasma Elafin in Psoriasis Diagnosis and Severity Assessment

Advanced Science, EarlyView.
The fully automated CLIA demonstrates high sensitivity and specificity for plasma Elafin, achieving 88% diagnostic accuracy and an AUC of 0.92 for psoriasis detection in a multicenter cohort. The assay reliably distinguishes psoriasis from other dermatoses, objectively stratifies disease severity, and allows longitudinal monitoring, supporting its ...
Jingkun Yi, Meng Xu, Ling Han, Zhining Dong, Ruimin Liu, Xiaomei Zhang, Di Hu, Chuanjian Lu, Xiaobo Yu   +8 more
wiley   +1 more source