Characterization of Prurigo Nodules in Adults With Moderate-To-Severe Atopic Dermatitis in Japan: A 2-Year Observational Study. [PDF]
Kataoka Y +8 more
europepmc +1 more source
This scoping review synthesizes evidence on atopic dermatitis (AD), psoriasis, and hidradenitis suppurativa in North American Indigenous peoples across 49 studies and 63 clinical trials. Findings reveal consistently high disease burden in AD, marked underrepresentation in trials and guidelines, and five evidence‐based recommendations to advance ...
Rachel Asiniwasis +17 more
wiley +1 more source
Real-World Evidence of Upadacitinib in Atopic Dermatitis after Inadequate Response or Intolerance to Dupilumab: The CAN UpTIMISE Study. [PDF]
Prajapati VH +10 more
europepmc +1 more source
Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller +11 more
wiley +1 more source
Development of a Conceptual Disease Model of Atopic Dermatitis Using Data from the Phase 3 ARCADIA 1 Trial. [PDF]
Silverberg JI +13 more
europepmc +1 more source
This 16‑week study assessed impact of dupilumab on skin barrier function in patients with moderate‑to‑severe atopic dermatitis (AD). Tape‑stripped stratum corneum samples for multi‑omic profiling, alongside transepidermal water loss measurements, were collected from lesional/non‑lesional AD skin and healthy controls at seven time points.
Taoming Liu +21 more
wiley +1 more source
Achieving Minimal Disease Activity in Atopic Dermatitis Is Associated with Fewer Flares, Reduced Healthcare Resource Utilization, and Improved Disease Control: Analysis from the Real-World MEASURE-AD Study. [PDF]
Silverberg JI +12 more
europepmc +1 more source
Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley +1 more source
Rezpegaldesleukin and Regulatory T Cell Restoration in Immune-Mediated Skin Diseases. [PDF]
Domingues J +3 more
europepmc +1 more source
Educational Artificial Intelligence Software to Support Assessment of Atopic Dermatitis Severity
ABSTRACT Accurate assessment of the severity of atopic dermatitis is crucial for guiding treatment. However, the Eczema Area and Severity Index (EASI), a widely used clinical assessment tool, relies on subjective visual scoring, which can lead to inter‐rater variability. This study aimed to evaluate the performance of convolutional neural network‐based
Kenichi Yamanaka +6 more
wiley +1 more source

