Results 1 to 10 of about 134,252 (360)

Association between pruritus and serum concentrations of parathormone, calcium and phosphorus in hemodialysis patients. [PDF]

, 2013
Chronic renal disorders have a progressive course in most cases, and finally result in end-stage renal disease (ESRD). Hemodialysis (HD) is one of the mainstays in the treatment of these patients. Disturbance in calcium (Ca) and phosphorus (P) metabolism
Bayzayi, F., Haddad, M., Joshaghani, H.R., Qorbani, M., Tajbakhsh, R.   +4 more
core   +5 more sources

Scratching increases epidermal neuronal branching and alters psychophysical testing responses in atopic dermatitis and brachioradial pruritus

Frontiers in Molecular Neuroscience, 2023
BackgroundChronic scratching imposes a major stress on the skin and can lead to itch intensity worsening, and consequently, patients may enter an itch–scratch cycle.
Lina Renkhold, Henning Wiegmann, Bettina Pfleiderer, Aysenur Süer, Claudia Zeidler, Manuel P. Pereira, Manuel P. Pereira, Martin Schmelz, Sonja Ständer, Konstantin Agelopoulos   +9 more
doaj   +1 more source

A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. [PDF]

, 2019
Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies.
Apostol, George, Bacon, Bruce, Bowlus, Christopher L, Dorenbaum, Alejandro, Gu, Joan, Hirschfield, Gideon M, Jones, David, Kennedy, Ciara, Levy, Cynthia, Luketic, Velimir, Mayo, Marlyn J, Medendorp, Sharon, Novak, Patricia, Patanwala, Imran, Pockros, Paul J, Vuppalanchi, Raj   +15 more
core   +2 more sources

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]

, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco, Francis, Heather, Kennedy, Lindsey, Kundu, Debjyoti, Meadows, Vik   +4 more
core   +1 more source

Emerging Methods to Objectively Assess Pruritus in Atopic Dermatitis. [PDF]

, 2019
INTRODUCTION:Atopic dermatitis (AD) is an inflammatory skin disease with a chronic, relapsing course. Clinical features of AD vary by age, duration, and severity but can include papules, vesicles, erythema, exudate, xerosis, scaling, and lichenification.
Bhutani, Tina, Liao, Wilson, Ly, Karen, Smith, Mary Patricia, Thibodeaux, Quinn, Weerasinghe, Thulasi, Wu, Jashin J, Yosipovitch, Gil   +7 more
core   +1 more source

Pathological Skin Picking: Case Presentation and Review of the Literature [PDF]

, 2015
Pathological skin picking is a condition in which patients induce skin lesions through repetitive, compulsive excoriations of normal skin or skin with minor surface irregularities and they admit their role in the production of the lesions, but are unable
Benea, Vasile, Georgescu, Simona Roxana, Leahu, Diana, Raileanu, Cristina, Sarbu, Maria Isabela, Tampa, Mircea   +5 more
core   +6 more sources

The Neuromodulatory Effect of Antipruritic Treatment of Chronic Prurigo

Dermatology and Therapy, 2019
Chronic prurigo is an extremely severe pruritic skin disease which presents with multiple, hyperkeratotic and erosive papules, nodules and/or plaques.
Claudia Zeidler, Manuel Pereira, Sonja Ständer   +2 more
doaj   +1 more source

Hand Pruritus: Clinical Profile, Functional Impairment and Disease-related Burden in a Prospective Cohort Study of 395 Patients

Acta Dermato-Venereologica, 2021
Human hands are complex structures essential for a variety of functions in everyday life. This study prospectively investigated the clinical features of hand pruritus and the resulting functional impairment and disease-related burden in 395 patients with
Teresa Gabriele Nau, Viola Rau, Claudia Zeidler, Sonja Ständer, Manuel P. Pereira   +4 more
doaj   +1 more source

Pruritus in Autoimmune and Inflammatory Dermatoses

Frontiers in Immunology, 2019
Pruritus in autoimmune and inflammatory dermatoses is a common symptom that can be severe and affect the quality of life of patients. In some diseases, pruritus is related to disorders activity and severity or may occur independent of the disease ...
Claudia Zeidler, Manuel Pedro Pereira, Flavien Huet, Flavien Huet, Laurent Misery, Laurent Misery, Kerstin Steinbrink, Sonja Ständer   +7 more
doaj   +1 more source

Obeticholic acid for the treatment of primary biliary cholangitis in adult patients: clinical utility and patient selection. [PDF]

, 2016
Primary biliary cholangitis (PBC), previously known as primary biliary "cirrhosis", is a rare autoimmune liver disease characterized by the hallmark autoantibodies to mitochondrial antigens and immune-mediated destruction of small bile duct epithelial ...
Bowlus, Christopher L
core   +3 more sources