Results 1 to 10 of about 2,133 (164)

Prurigo Nodularis at Ultra-High-Frequency Ultrasound [PDF]

open access: yesDiagnostics
Here, we describe the case of a 48-year-old female patient with prurigo nodularis, where B-mode and color-Doppler ultrasound of one nodule was performed; this revealed hypoechoic dermal and hyperechoic epidermal thickening with lesion hypervascularity ...
Alessandra Michelucci   +11 more
doaj   +2 more sources

Tofacitinib for Prurigo Nodularis: A Case Report

open access: yesClinical, Cosmetic and Investigational Dermatology, 2022
Changlan Peng,1 Chunxiao Li,2 Yingying Zhou,1 Qiuyue Wang,1 Ping Xie,1 Tianhao Li,2,* Pingsheng Hao2,* 1Department of Dermatology, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Dermatology,
Ping-Sheng Hao   +2 more
exaly   +2 more sources

Successful treatment of refractory prurigo nodularis with abrocitinib

open access: yesClinical Case Reports (discontinued)
Key Clinical Message Prurigo nodularis is frequently difficult to manage with conventional therapy. Given the pathogenesis and refractory nature, we demonstrate a case in which inhibition of JAK–STAT signaling may significantly improve prurigo nodularis.
Zhenzhen Wu
exaly   +2 more sources

Dupilumab for the treatment of prurigo nodularis: A systematic review

open access: yesFrontiers in Immunology, 2023
BackgroundConventional treatment techniques have limited efficacy and more side effects in the treatment of prurigo nodularis. The better alternative treatment option for better outcomes of the disease is dupilumab.ObjectiveThe objective of this study ...
Zhang Litao
exaly   +3 more sources

Cost-effectiveness Analysis of Dupilumab for the Treatment of Adult Patients with Severe Prurigo Nodularis in Italy [PDF]

open access: yesActa Dermato-Venereologica
Prurigo nodularis is characterized by intensely pruritic nodules that significantly impact patients’ quality of life. This study aims to evaluate the cost-effectiveness of dupilumab compared with the best supportive care for the treatment of severe ...
Cataldo Patruno   +6 more
doaj   +2 more sources

Safety, Pharmacokinetics, and Efficacy of 1.5% Ruxolitinib Gel (HDM3010) in Adult Patients with Prurigo Nodularis: A Phase I/II, Randomized, Double-Blind, Vehicle-Controlled Multicenter Clinical Trial [PDF]

open access: yesDermatology and Therapy
Introduction Prurigo nodularis (PN) is a chronic inflammatory dermatosis with severe, persistent pruritus and limited effective therapies. Janus kinase (JAK) inhibition has emerged as a targeted strategy for PN.
Chao Wu   +28 more
doaj   +2 more sources

Successful Treatment of Pediatric Atopic Prurigo Nodularis with Dupilumab [PDF]

open access: yesClinical, Cosmetic and Investigational Dermatology
Yuping Zhang,* Lizhu Liang,* Chen Li Department of Dermatology, Zhongshan City People’s Hospital, Zhongshan City, Guangdong Province, 528403, People’s Republic of China*These authors contributed equally to this workCorrespondence:
Zhang Y, Liang L, Li C
doaj   +2 more sources

Immunotargets and Therapy for Prurigo Nodularis

open access: yesImmunoTargets and Therapy, 2022
Angelina Labib, Teresa Ju, Ashley Vander Does, Gil Yosipovitch Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery and Miami Itch Center, University of Miami Miller School of Medicine, Miami, FL, USACorrespondence: Gil Yosipovitch, Dr ...
, TERESA Ju, Angelina Labib
exaly   +2 more sources

Effective Treatment of Prurigo Nodularis With Oral Tofacitinib: A Case Report [PDF]

open access: yesClinical Case Reports
Recent advancements in understanding the potential pathogenesis of prurigo nodularis (PN) have paved the way for the development of new, targeted therapies.
Nikoo Mozafari
doaj   +2 more sources

Impact of Chronic Kidney Disease Severity on the Risk of Prurigo Nodularis: A Population-Based Cohort Study

open access: yesActa Dermato-Venereologica, 2022
While dialysis is linked with prurigo nodularis, little is known about the impact of non-dialysis chronic kidney disease on prurigo nodularis. The influence of chronic kidney disease on development of prurigo nodularis was measured using the Korean ...
Hei Sung Kim   +2 more
doaj   +1 more source

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