Results 31 to 40 of about 4,117 (197)

Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor β antibody, in moderate-to-severe prurigo nodularis: a randomised, double-blind, placebo-controlled, phase 2a studyResearch in context

open access: yesEClinicalMedicine, 2023
Summary: Background: Prurigo nodularis is a chronic skin disease characterised by intensely pruritic, hyperkeratotic nodules. Vixarelimab, a human monoclonal antibody, binds to the beta subunit of the oncostatin M receptor, inhibiting signalling of both
Howard Sofen   +10 more
doaj   +1 more source

Chronic Prurigo: Similar Clinical Profile and Burden Across Clinical Phenotypes

open access: yesFrontiers in Medicine, 2021
Chronic prurigo is a debilitating skin disease characterized by the presence of chronic pruritus and scratching-related pruriginous lesions. The pruriginous lesions can differ in their clinics what has recently been categorized into different clinical ...
Claudia Zeidler   +2 more
doaj   +1 more source

Juvenile pemphigoid nodularis: Report of a rare case

open access: yesIndian Dermatology Online Journal, 2014
Bullous pemphigoid is an autoimmune blistering disease that is rare in childhood. Pemphigoid nodularis is a variant of BP that is exceedingly rare in children.
Dipti Das, Debabrata Bandyopadhyay
doaj   +1 more source

Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study

open access: yesActa Dermato-Venereologica, 2020
Prurigo nodularis is a pruritic dermatosis with poor treatment options. To describe treatment patterns, comorbidities, pruritus, and quality of life a survey was administered to 92 patients with prurigo nodularis.
Tanja Todberg   +2 more
doaj   +1 more source

Chronic Prurigo: An Unusual Presentation of Hodgkin Lymphoma

open access: yesCase Reports in Dermatology, 2018
Background: Prurigo nodularis is a condition of unknown origin defined by papulonodular eruption and intense pruritus. Hodgkin lymphoma often presents nonspecific initial symptoms.
Shireen Dumont   +2 more
doaj   +1 more source

Increased β‐endorphin and autotaxin in patients with prurigo

open access: yesJournal of Cutaneous Immunology and Allergy, 2019
Objectives Prurigo is a treatment‐resistant inflammatory disease of unknown etiology. Persistent and severe itch is a major and important clinical symptom, but pathological mechanisms and/or actual mediators for itch in prurigo remain to be defined ...
Takahiro Ishikawa   +4 more
doaj   +1 more source

Case Report: Pemphigoid Nodularis—Five Patients With Many Years of Follow-Up and Review of the Literature

open access: yesFrontiers in Immunology, 2022
Pemphigoid nodularis is a rare form of pemphigoid that joins the clinical picture of prurigo nodularis and the immunological features of bullous pemphigoid, which is therapeutically challenging.
Konrad Szymanski   +5 more
doaj   +1 more source

Dupilumab for the treatment of prurigo nodularis: A systematic review

open access: yesFrontiers in Immunology, 2023
BackgroundConventional treatment techniques have limited efficacy and more side effects in the treatment of prurigo nodularis. The better alternative treatment option for better outcomes of the disease is dupilumab.ObjectiveThe objective of this study ...
Peng Cao   +6 more
doaj   +1 more source

Trial of Nemolizumab in Moderate-to-Severe Prurigo Nodularis

open access: yes, 2020
Prurigo nodularis is a chronic pruritic skin disease with multiple nodular skin lesions. Nemolizumab is a monoclonal antibody targeting the interleukin-31 receptor, which is involved in the pathogenesis of prurigo nodularis.
Wollenberg, Andreas   +11 more
core   +1 more source

Fototerapia en el prurigo nodular. Experiencia propia y revisión de la literatura

open access: yesActas Dermo-Sifiliográficas, 2021
Resumen: Antecedentes y objetivo: El prurigo nodular (PN) es una dermatosis inflamatoria crónica caracterizada por la presencia de lesiones nodulares, intensamente pruriginosas, con gran impacto en la calidad de vida. El intenso prurito y el rascado son
A. Arrieta   +4 more
doaj   +1 more source

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