Results 31 to 40 of about 2,123 (172)

Aberrant Expression of Histamine-independent Pruritogenic Mediators in Keratinocytes may be Involved in the Pathogenesis of Prurigo Nodularis

open access: yesActa Dermato-Venereologica, 2019
Prurigo nodularis is a highly pruritic and hyperplastic chronic dermatosis with unknown pathogenesis. Many pruritogenic mediators, including nerve growth factor, interleukin (IL)-31, thymic stromal lymphopoietin, and endothelin-1, are implicated in ...
Weilong Zhong   +9 more
doaj   +1 more source

Dermatoscopic features of prurigo nodularis

open access: yesIndian Dermatology Online Journal, 2019
Pragya A Nair, Trusha Patel
doaj   +3 more sources

Out‐of‐pocket expenditures in adult patients with prurigo nodularis in France

open access: yesJEADV Clinical Practice, 2023
Background Chronic prurigo or prurigo nodularis is a severe condition with chronic pruritus and skin lesions. Current unnmet medical needs are numerous and generate a significant burden for the patients.
Laurent Misery   +6 more
doaj   +1 more source

Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor β antibody, in moderate-to-severe prurigo nodularis: a randomised, double-blind, placebo-controlled, phase 2a studyResearch in context

open access: yesEClinicalMedicine, 2023
Summary: Background: Prurigo nodularis is a chronic skin disease characterised by intensely pruritic, hyperkeratotic nodules. Vixarelimab, a human monoclonal antibody, binds to the beta subunit of the oncostatin M receptor, inhibiting signalling of both
Howard Sofen   +10 more
doaj   +1 more source

Chronic Prurigo: Similar Clinical Profile and Burden Across Clinical Phenotypes

open access: yesFrontiers in Medicine, 2021
Chronic prurigo is a debilitating skin disease characterized by the presence of chronic pruritus and scratching-related pruriginous lesions. The pruriginous lesions can differ in their clinics what has recently been categorized into different clinical ...
Claudia Zeidler   +2 more
doaj   +1 more source

Juvenile pemphigoid nodularis: Report of a rare case

open access: yesIndian Dermatology Online Journal, 2014
Bullous pemphigoid is an autoimmune blistering disease that is rare in childhood. Pemphigoid nodularis is a variant of BP that is exceedingly rare in children.
Dipti Das, Debabrata Bandyopadhyay
doaj   +1 more source

Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study

open access: yesActa Dermato-Venereologica, 2020
Prurigo nodularis is a pruritic dermatosis with poor treatment options. To describe treatment patterns, comorbidities, pruritus, and quality of life a survey was administered to 92 patients with prurigo nodularis.
Tanja Todberg   +2 more
doaj   +1 more source

Chronic Prurigo: An Unusual Presentation of Hodgkin Lymphoma

open access: yesCase Reports in Dermatology, 2018
Background: Prurigo nodularis is a condition of unknown origin defined by papulonodular eruption and intense pruritus. Hodgkin lymphoma often presents nonspecific initial symptoms.
Shireen Dumont   +2 more
doaj   +1 more source

Increased β‐endorphin and autotaxin in patients with prurigo

open access: yesJournal of Cutaneous Immunology and Allergy, 2019
Objectives Prurigo is a treatment‐resistant inflammatory disease of unknown etiology. Persistent and severe itch is a major and important clinical symptom, but pathological mechanisms and/or actual mediators for itch in prurigo remain to be defined ...
Takahiro Ishikawa   +4 more
doaj   +1 more source

Case Report: Pemphigoid Nodularis—Five Patients With Many Years of Follow-Up and Review of the Literature

open access: yesFrontiers in Immunology, 2022
Pemphigoid nodularis is a rare form of pemphigoid that joins the clinical picture of prurigo nodularis and the immunological features of bullous pemphigoid, which is therapeutically challenging.
Konrad Szymanski   +5 more
doaj   +1 more source

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