Results 11 to 20 of about 2,123 (172)

Prurigo nodularis

Journal of the American Academy of Dermatology, 2020
Prurigo nodularis. Prurigo nodularis is the most severe degree of chronic prurigo. Disseminated nodules (mostly on the 4 members) are associated with skin excoriations and an intense pruritus. Whatever the etiology, prurigo nodularis is autonomous disease which is related to itch sensitization (similar to pain sensitization). The burden is high.
Amy H Huang, Micah Belzberg, Shawn G Kwatra   +2 more
exaly   +7 more sources

Prurigo Nodularis at Ultra-High-Frequency Ultrasound [PDF]

Diagnostics
Here, we describe the case of a 48-year-old female patient with prurigo nodularis, where B-mode and color-Doppler ultrasound of one nodule was performed; this revealed hypoechoic dermal and hyperechoic epidermal thickening with lesion hypervascularity ...
Alessandra Michelucci, Corrado Tagliati, Flavia Manzo Margiotta, Giorgia Salvia, Marco Fogante, Giulio Rizzetto, Antonio Corvino, Elisa Molinelli, Annamaria Offidani, Oriana Simonetti, Marco Romanelli, Valentina Dini   +11 more
doaj   +2 more sources

Tofacitinib for Prurigo Nodularis: A Case Report

Clinical, Cosmetic and Investigational Dermatology, 2022
Changlan Peng,1 Chunxiao Li,2 Yingying Zhou,1 Qiuyue Wang,1 Ping Xie,1 Tianhao Li,2,* Pingsheng Hao2,* 1Department of Dermatology, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Dermatology,
Changlan Peng, Qiuyue Wang, Pingsheng Hao   +2 more
exaly   +2 more sources

Cost-effectiveness Analysis of Dupilumab for the Treatment of Adult Patients with Severe Prurigo Nodularis in Italy [PDF]

Acta Dermato-Venereologica
Prurigo nodularis is characterized by intensely pruritic nodules that significantly impact patients’ quality of life. This study aims to evaluate the cost-effectiveness of dupilumab compared with the best supportive care for the treatment of severe ...
Cataldo Patruno, Massimiliano Povero, Andrea Tassone, Maria Paola Pedone, Donia Bahloul, Jules Tavi, Paolo Amerio   +6 more
doaj   +2 more sources

Successful treatment of refractory prurigo nodularis with abrocitinib

Clinical Case Reports (discontinued)
Key Clinical Message Prurigo nodularis is frequently difficult to manage with conventional therapy. Given the pathogenesis and refractory nature, we demonstrate a case in which inhibition of JAK–STAT signaling may significantly improve prurigo nodularis.
Zhenzhen Wu
exaly   +2 more sources

Safety, Pharmacokinetics, and Efficacy of 1.5% Ruxolitinib Gel (HDM3010) in Adult Patients with Prurigo Nodularis: A Phase I/II, Randomized, Double-Blind, Vehicle-Controlled Multicenter Clinical Trial [PDF]

Dermatology and Therapy
Introduction Prurigo nodularis (PN) is a chronic inflammatory dermatosis with severe, persistent pruritus and limited effective therapies. Janus kinase (JAK) inhibition has emerged as a targeted strategy for PN.
Chao Wu, Xuping Niu, Xiaohua Wang, Juan Su, Hengguang Zhao, Mao Lin, Chunjun Yang, Xiaoming Qin, Shuping Guo, Cunhuo Jiang, Hui Tang, Haijing Yang, Liming Wu, Min Zhu, Aihua Wei, Xiaohua Tao, Yiwen Zhang, Chang Shu, Jiawei Liu, Lu Yang, Yuetong Qian, Bingjie Zhang, Shiyu Zhang, Junfang Xu, Yang Lu, Mingjia Peng, Shizheng Luo, Weijie Ma, Hongzhong Jin   +28 more
doaj   +2 more sources

Successful Treatment of Pediatric Atopic Prurigo Nodularis with Dupilumab [PDF]

Clinical, Cosmetic and Investigational Dermatology
Yuping Zhang,* Lizhu Liang,* Chen Li Department of Dermatology, Zhongshan City People’s Hospital, Zhongshan City, Guangdong Province, 528403, People’s Republic of China*These authors contributed equally to this workCorrespondence:
Zhang Y, Liang L, Li C
doaj   +2 more sources

Immunotargets and Therapy for Prurigo Nodularis

ImmunoTargets and Therapy, 2022
Angelina Labib, Teresa Ju, Ashley Vander Does, Gil Yosipovitch Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery and Miami Itch Center, University of Miami Miller School of Medicine, Miami, FL, USACorrespondence: Gil Yosipovitch, Dr ...
Angelina Labib, TERESA Ju, Ashley Vander Does   +2 more
exaly   +2 more sources

Impact of Chronic Kidney Disease Severity on the Risk of Prurigo Nodularis: A Population-Based Cohort Study

Acta Dermato-Venereologica, 2022
While dialysis is linked with prurigo nodularis, little is known about the impact of non-dialysis chronic kidney disease on prurigo nodularis. The influence of chronic kidney disease on development of prurigo nodularis was measured using the Korean ...
Hei Sung Kim, Hyun Jung Kim, Hyeong Sik Ahn   +2 more
doaj   +1 more source

Early-onset, severe prurigo nodularis in a young child with atopic dermatitis treated successfully with dupilumab

Indian Journal of Paediatric Dermatology, 2022
Prurigo nodularis is an extremely pruritic skin condition as a result of chronic and vicious cycle of itching and scratching. It is rare in children. We report a case of a 4-year-old child with a background of poorly controlled atopic dermatitis with ...
Henrietta Albela, Kin Fon Leong
doaj   +1 more source