Results 31 to 40 of about 81,111 (166)

Chronic Itch Affects Patients’ Ability to Experience Pleasure: Anhedonia in Itchy Disorders

Acta Dermato-Venereologica
Anhedonia, the reduced ability to experience pleasure, is a prevalent symptom in various psychiatric disorders, but has not been investigated in dermatological conditions, particularly those characterized by chronic itch.
Aleksandra Stefaniak, Magdalena Berek-Zamorska, Claudia Zeidler, Sonja Ständer, Jacek C. Szepietowski   +4 more
doaj   +1 more source

Quality of Life in Psoriasis Vulgaris: Use of the ItchyQoL Question­naire in a Secukinumab Phase III Trial in Patients with Psoriasis Vulgaris

Acta Dermato-Venereologica, 2019
Chronic pruritus is a bothersome symptom in psoriasis vulgaris and can profoundly reduce quality of life (QoL). In this exploratory analysis of the PSORITUS study, the impact of pruritus on QoL in 130 subjects with moderate-to-severe psoriasis was ...
Sonja Ständer, Sabine Steinke, Matthias Augustin, Dieter Metze, Karin Loser, Daniel Baeumer, Christian Sieder, Thomas Luger   +7 more
doaj   +1 more source

Chronic Pruritus in the Absence of Skin Disease: A Retrospective Study of 197 French Inpatients

Acta Dermato-Venereologica, 2020
Chronic pruritus (CP) can occur in the absence of skin diseases, and may be secondary to various causes. The aim of this study was to retrospectively analyse the causes of CP without skin disease in a cohort of patients from the dermatology department ...
Marine Robert, Laurent Misery, Emilie Brenaut   +2 more
doaj   +1 more source

Content Validity and Psychometric Validation of an Adapted Version of the Subject Sleep Diary in Prurigo Nodularis

Dermatology and Therapy
Introduction Patients with prurigo nodularis (PN) often experience sleep disturbance. A psychometric evaluation was conducted to assess the suitability of a PN-adapted multi-item subject sleep diary (SSD) for measuring PN-related sleep disturbance ...
Sonja Ständer, Danielle N. Rodriguez, Carla Dias-Barbosa, Dina Filipenko, Jorge Puelles, Zarif K. Jabbar-Lopez, Christophe Piketty, Henning Wiegmann, Shawn G. Kwatra   +8 more
doaj   +1 more source

Validation of the Itch Severity Item as a Measurement Tool for Pruritus in Patients with Psoriasis: Results from a Phase 3 Tofacitinib Program

Acta Dermato-Venereologica, 2017
Tofacitinib is an oral Janus kinase inhibitor. This post-hoc analysis aimed to investigate the psychometric properties of the Itch Severity Item (ISI), a numeric rating scale from 0 (no itching) to 10 (worst possible itching) for pruritus in psoriasis ...
Sonja Ständer, Thomas Luger, Joseph C. Cappelleri, Andrew G. Bushmakin, Carla Mamolo, Michael A. Zielinski, Anna M Tallman, Gil Yosipovitch   +7 more
doaj   +1 more source

Koebnerization of Hailey–Hailey disease into chronic prurigo nodularis: Clearance of both entities under a naloxone therapy

JEADV Clinical Practice
Hailey–Hailey disease (HHD) is a genetic skin disorder, accompanied by lesional pruritus and a relevant impact on quality of life of affected patients. Approved or even successful treatments are still lacking, highlighting the need for further insight in
Felix Witte, Dieter Metze, Sonja Ständer, Claudia Zeidler   +3 more
doaj   +1 more source

Brachioradial Pruritus and Notalgia Paraesthetica: A Comparative Observational Study of Clinical Presentation and Morphological Pathologies

Acta Dermato-Venereologica, 2017
Brachioradial pruritus (BRP) and notalgia paraesthetica (NP) represent 2 of the most common neuropathic itch syndromes. A total of 58 consecutive patients presenting at the Center for Chronic Pruritus, University Hospital Münster, were analysed with ...
Manuel P. Pereira, Hannah Lüling, Annette Dieckhöfer, Sabine Steinke, Claudia Zeidler, Sonja Ständer   +5 more
doaj   +1 more source

Investigator’s Global Assessment of Chronic Prurigo: A New Instrument for Use in Clinical Trials

Acta Dermato-Venereologica, 2021
Chronic prurigo is a pruritic disease characterized by the development of pruriginous lesions due to scratching. The number of lesions is representative of the stage of the disease, while the presence of excoriations reflects the scratching activity. Aim
Claudia Zeidler, Manuel P. Pereira, Matthias Augustin, Mary Spellman, Sonja Ständer   +4 more
doaj   +1 more source

Dupilumab versus Lebrikizumab Demonstrates Greater Likelihood of Achieving and Maintaining Improvements in Efficacy Outcomes Using a Placebo-Adjusted Indirect Treatment Comparison

Dermatology and Therapy
Introduction Dupilumab and lebrikizumab have demonstrated efficacy in atopic dermatitis (AD) clinical trials; however, no direct comparisons exist. Methods Efficacy outcome achievement (dupilumab and lebrikizumab with topical corticosteroids [TCS]) at 16 
Sonja Ständer, Andreas Pinter, Firas G. Hougeir, Patricia Guyot, Yingxin Xu, Amy H. Praestgaard, Nick Freemantle, Ana B. Rossi, Gaëlle Bégo-Le-Bagousse, Zhixiao Wang, Kerry Noonan, Mike Bastian   +11 more
doaj   +1 more source

Treatment Preferences Among Systemic Therapy-Naïve Patients with Atopic Dermatitis or Psoriasis in Germany: A Multicentre Study

Dermatology and Therapy
Introduction Despite the expanding range of approved systemic therapies for atopic dermatitis (AD) and psoriasis (PSO), data on patient preferences remain limited. It is largely unknown whether patients wish to initiate systemic treatment, which route of
Svenja Royeck, Anna Daphne Bamidis, Conrad Weckbecker, Silke C. Hofmann, Sonja Ständer, Natalija Novak, Galina Balakirski, Dagmar Wilsmann-Theis   +7 more
doaj   +1 more source