Results 171 to 180 of about 18,084 (203)
Some of the next articles are maybe not open access.
Journal of the American Statistical Association, 1979
Abstract To explore the possibility that robust estimators of location can be adapted to the problem of estimating the ED50 in binary-response bioassay, 10 estimators are compared. A Monte Carlo study is conducted to determine the mean squared errors (MSE) of the estimators. Taking into account the MSE for a variety of symmetric tolerance distributions,
openaire +1 more source
Abstract To explore the possibility that robust estimators of location can be adapted to the problem of estimating the ED50 in binary-response bioassay, 10 estimators are compared. A Monte Carlo study is conducted to determine the mean squared errors (MSE) of the estimators. Taking into account the MSE for a variety of symmetric tolerance distributions,
openaire +1 more source
Trimmed Logit Method for Estimating the ED50 in Quantal Bioassay
Biometrics, 1987Trimmed nonparametric procedures such as the trimmed Spearman-Karber method have been proposed in the literature for overcoming the deficiencies of the probit and logit models in the analysis of quantal bioassay data. However, there are situations where the median effective dose (ED50) is not calculable with the trimmed Spearman-Karber method, but is ...
L P, Sanathanan +2 more
openaire +2 more sources
ED50 and Recovery Times After Propofol in Rats with Graded Cirrhosis
Anesthesia & Analgesia, 2012Patients with end-stage liver disease have increased sensitivity to general anesthetics. In this study, we sought to quantify sensitivity to propofol as a function of the degree of liver disease, in a rat model of cirrhosis.Liver disease was induced by carbon tetrachloride (CCl(4)) injections for 6, 9, or 12 weeks in 3 study groups.
Zhenzhou, Li +6 more
openaire +2 more sources
Litchfield and Wilcoxon I: Confidence Limits of ED50
1987The use of the probit conversion for drawing smooth quantal log dose—effect curves was discussed in Procedure 9. Since there are no values of the probit corresponding to 0 and 100% effects the method of Procedure 9 does not handle such complete log dose—effect curves.
Ronald J. Tallarida, Rodney B. Murray
openaire +1 more source
1970
Mochte man die kleinste Dosis einer Substanz, die bei einem Tier imstande ist, eine bestimmte Reaktion auszulosen, bestimmen, so konnte man folgendermasen vorgehen: Man legt dem Tier eine Infusion an und stoppt diese, wenn die Reaktion eintritt: Die eingelaufene Substanzmenge stellt fur dieses Tier dann die Schwellendosis dar (sog.
openaire +1 more source
Mochte man die kleinste Dosis einer Substanz, die bei einem Tier imstande ist, eine bestimmte Reaktion auszulosen, bestimmen, so konnte man folgendermasen vorgehen: Man legt dem Tier eine Infusion an und stoppt diese, wenn die Reaktion eintritt: Die eingelaufene Substanzmenge stellt fur dieses Tier dann die Schwellendosis dar (sog.
openaire +1 more source
ED50 of desflurane for laryngeal mask airway removal in anaesthetised adults
Anaesthesia, 2011Summary Previous estimates for the end‐tidal concentration of desflurane that allows removal of the laryngeal mask airway in 50% of anaesthetised adults (ED50) have ranged from 2.1% to 5.3%. To assess which value is correct, we studied 32 female patients (aged 30–50 years) undergoing intracavity caesium implants ...
J K, Makkar, S, Arora, K, Jain, J, Wig
openaire +2 more sources
Determination of ED50 of Hydromorphone for Postoperative Analgesia Following Cesarean Delivery
Survey of Anesthesiology, 2016Morphine is the most common opioid injected into the intrathecal space for postoperative analgesia following cesarean delivery, but ongoing medication shortages have resulted in limited availability. One proposed morphine alternative is hydromorphone. Studies investigating its use in post-cesarean analgesia are limited.
openaire +2 more sources
ED50 and ED90 of intrathecal hyperbaric 2% prilocaine in ambulatory knee arthroscopy
Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2014Hyperbaric 2% prilocaine (HP) is increasingly used for spinal anesthesia in day-case surgery. The aim of this prospective double-blind study was to determine the effective dose (ED)50 and the ED90 of HP for patients undergoing knee arthroscopy.Doses of HP were determined using an up-and-down sequential allocation technique.
Guntz, Emmanuel +4 more
openaire +2 more sources
A computer program in BASIC for estimation of ED50 and LD50
Computers in Biology and Medicine, 1989A BASIC computer program for calculating ED50 and LD50 values and their confidence limits by probit analysis and weighted linear regression is presented. It also includes the Chi square procedure for testing the mathematical model and allows on-screen high resolution graphic display.
openaire +2 more sources
Porcine skin ED50 damage thresholds for 1214 nm laser irradiation
SPIE Proceedings, 2008A series of experiments were conducted in vivo on porcine skin to determine the ED50 damage thresholds for 1214 nm continuous wave laser irradiation. These results provide new information for refinement of Maximum Permissible Exposure (MPE). The study employed exposure durations of 1 sec, 3 sec, and 10 seconds with nominal spot diameters of 6 mm, 8 mm ...
Bo Chen +5 more
openaire +1 more source