Results 131 to 140 of about 40,104 (329)

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source

EDC, uporabniki in Internet

, 1996
Nove tehnologije in novi nosilci informacij so prinesli spremembe v knjižnico. Avtor na primeru Evropskega dokumentacijskega centra v Univerzitetni knjižnici Maribor govori o prednostih in omejitvah uporabe Interneta. Ugotavlja tudi potrebnost informacijskih specialistov.
openaire   +2 more sources

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, EarlyView.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source

Revision of task description of educational development centers and educational development offices: Toward performance improvement

Journal of Education and Health Promotion
BACKGROUND: In recent years, educational development centers (EDCs) have evolved among universities from a marginal to a strategic aspect. The present study aimed to achieve an applicable task description at two levels of basic and quality improvement ...
Maria Shaterjalali, Nikoo Yamani, Aeen Mohammadi   +2 more
doaj   +1 more source

The Study of Differences in EDCs perception between smokers and nonsmokers

, 2018
This study utilizes an perception survey result of EDCs(Endocrine Disrupting Chemicals), and in order to compare the difference between EDCs perception levels as per smokers and nonsmokers.
임영욱, 이용진
core  

Identification of Linkages between EDCs in Personal Care Products and Breast Cancer through Data Integration Combined with Gene Network Analysis

, 2017
Approximately 1000 chemicals have been reported to possibly have endocrine disrupting effects, some of which are used in consumer products, such as personal care products (PCPs) and cosmetics.
Hyeri Jeong, Jongwoon Kim, Youngjun Kim
core   +1 more source

Heat‐Suppressing Projection Two‐Photon Lithography Enables High‐Throughput Sub‐Micrometer Manufacturing of Biopolymer Hydrogels for Tissue Engineering

Advanced Science, EarlyView.
The iLEAP technique integrates high‐throughput two‐photon lithography with extrusion printing, bridging sub‐micrometer precision and macroscopic scaffold fabrication. By employing a low‐exothermic photoinitiator, it mitigates thermal damage to biopolymers and preserves bioactivity.
Qifeng Guan, Yanzhe Fu, Xiangyu Xu, Naitao Li, Sen Hou, Kai Wang, Yufan Wang, Jiakun Li, Ping Li, Jiebo Li, Lizhen Wang, Yubo Fan   +11 more
wiley   +1 more source

Assessing species bias in amphibian research on endocrine disruptors: beyond Xenopus laevis

Frontiers in Environmental Science
Due to their high sensitivity to hormonal agents, in recent years, amphibians have been proposed as bioindicators for the presence of endocrine-disrupting compounds (EDCs) in the environment.
Martyna Frątczak, Mikołaj Kaczmarski, Katarzyna Szkudelska, Piotr Tryjanowski   +3 more
doaj   +1 more source

Effects of Endocrine Disrupting Chemicals on Cellular Function in Mouse Peritoneal Macrophages [PDF]

, 2004
We investegated the effects of nine possible endocrine disrupting chemicals (EDCs) on the nitric oxide (NO) production and growth of mouse peritoneal macrophages. Genistein and coumestrol inhibited lipopolysaccharide-induced NO production in macrophages,
シロサワ, エリ, ツツミ, ヒロム, ヨコタ, カツシ, Ebina, Keiichi, クマガイ, タケシ, 堤, 啓, 横田, 勝司, Yokota, Katsushi, Kumagai, Takeshi, 熊谷, 健, 蝦名, 敬一, Shirosawa, Eri, 白澤, 衣理, エビナ, ケイイチ, Tsutsumi, Hiromu   +14 more
core  

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source