Results 141 to 150 of about 40,104 (329)
Development of chemosensors for endocrine disrupting chemicals (EDCs): synthesis and evaluation of solid-phase bound receptors [PDF]
, 2009 Worldwide concern has been growing on the increasing distribution of endocrine disrupting chemicals (EDCs) during the last decade. The overall anxiety is caused by their effect on the endocrine system of wildlife and humans.
Van der Plas, Steven
core
A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau
Advanced Science, EarlyView.TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun +12 more
wiley +1 more source
Bio-inspired titania-based laccase biocatalyst for removal of EDCs
, 2013 The removal of micropollutants from wastewater, especially endocrine disrupting chemicals (EDCs), is one of the recent challenges in environmental protection.
Demarche, Philippe +2 more
core
Advanced Science, EarlyView.Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan +7 more
wiley +1 more source
Advanced Science, EarlyView.MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant +14 more
wiley +1 more source
The adverse role of endocrine disrupting chemicals in the reproductive system
Frontiers in EndocrinologyReproductive system diseases pose prominent threats to human physical and mental well-being. Besides being influenced by genetic material regulation and changes in lifestyle, the occurrence of these diseases is closely connected to exposure to harmful ...
Jing Pan +4 more
doaj +1 more source
QSAR classification of estrogen receptor binders and identification of pleiotropic EDCs
, 2010 Endocrine disrupting chemicals (EDCs) are suspected of posing serious threats to human and wildlife health through a variety of mechanisms, these being mainly 10 receptor-mediated modes of action. It is reported that some EDCs exhibit dual activities as
J. Li +3 more
core +1 more source
Advanced Science, EarlyView.An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu +10 more
wiley +1 more source
ToxicsBackground/Objectives: Endocrine-disrupting chemicals (EDCs) are exogenous substances that interfere with hormone regulation, leading to adverse health outcomes.
Esin Okman, Sıddika Songül Yalçın
doaj +1 more source
Advanced Science, EarlyView.A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu +7 more
wiley +1 more source