Results 181 to 190 of about 1,170,924 (343)

New insights into the mechanisms of pulmonary edema in acute lung injury.

Annals of Translational Medicine, 2018
R. Herrero, Gema Sánchez, J. Lorente
semanticscholar   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

Advanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen, Yiming Huang, Yang Zhang, Chunhao Yu, Hanqi Liu, Dong Bian, Di Wu, Wu Wang, Xunming Ji, Yufeng Zheng, Miaowen Jiang, Ming Li   +11 more
wiley   +1 more source

Correction to: Correlation analysis on serum inflammatory cytokine level and neurogenic pulmonary edema for children with severe hand–foot–mouth disease [PDF]

, 2018
Jinfang Sun, Hao-Lan Li, Bao-xia Sun
openalex   +1 more source

Effects of Intravitreal Aflibercept on Retinal Function and Improvement of Macular Edema Associated With Diabetic Retinopathy [PDF]

, 2020
Atsushi Ichio, Masahiko Sugimoto, Hisashi Matsubara, Daiki Mochida, Kumiko Kato, Mineo Kondo   +5 more
openalex   +1 more source

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

Cancer Cell, 2007
T. Batchelor, A. Sorensen, E. di Tomaso, Wei-Ting Zhang, D. Duda, K. Cohen, K. Kozak, D. Cahill, P. Chen, M. Zhu, M. Ancukiewicz, M. Mrugala, S. Plotkin, J. Drappatz, D. Louis, P. Ivy, D. Scadden, T. Benner, J. Loeffler, P. Wen, R. Jain   +20 more
semanticscholar   +1 more source

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

Advanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu, Jintao Song, Mengjiao Guo, RuZe Ma, Mingyang Du, Zhe Xun, Xu Liu, RongXia Xu, Xiaochun Xie, Peilin Qi, Yujie Chen, Dan Shao, Chao Yang, Liang Wang, Xiaoyu Song, Difei Wang   +15 more
wiley   +1 more source

Microglial Feimin Alleviates Cognitive Impairment in High‐Fat Diet‐Fed Mice

Advanced Science, EarlyView.
Microglial feimin deletion exacerbates lipotoxicity‐induced neuroinflammation and cognitive decline. In both in vitro and in vivo models, loss of feimin aggravated lipid droplet accumulation, IL‐1β/IL‐6 release, and neuronal injury through the PI3K–AKT–mTOR pathway, ultimately leading to severe neuronal apoptosis and cognitive impairment under high‐fat
Ran Gao, Zhonghua Xiong, Wenting Su, Jiahui Deng, Bin Zhai, Gaizhi Zhu, Min Zhang, Qi Zeng, Jinming Qiu, Ziqing Bian, He Xiao, Guoming Luan, Renxi Wang   +12 more
wiley   +1 more source

Myocardial Edema After Ischemia/Reperfusion Is Not Stable and Follows a Bimodal Pattern

, 2014
Rodrigo Fernández‐Jiménez, Javier Sánchez‐González, Jaume Agüero, Jaime García‐Prieto, Gonzalo J. López-Martín, José M. García‐Ruiz, Antonio Molina, Xavier Rosselló, Leticia Fernández‐Friera, Gonzalo Pizarro, Ana García‐Álvarez, Erica Dall’Armellina, Carlos Macaya, Robin P. Choudhury, Valentı́n Fuster, Borja Ibáñez   +15 more
openalex   +1 more source

Noncardiogenic Pulmonary Edema Induced by Radiocontrast Media [PDF]

, 2021
K. Nangrani, Robert J. Kowalsky, Annapurna Kumari, N. Mesiha, Louis Gerolemou   +4 more
openalex   +1 more source