Results 61 to 70 of about 967,040 (315)

TRPV1 Blocker HCRG21 Suppresses TNF-α Production and Prevents the Development of Edema and Hypersensitivity in Carrageenan-Induced Acute Local Inflammation

Biomedicines, 2021
Currently the TRPV1 (transient receptor potential vanilloid type 1) channel is considered to be one of the main targets for pro-inflammatory mediators including TNF-α.
Oksana Sintsova, Irina Gladkikh, Anna Klimovich, Yulia Palikova, Viktor Palikov, Olga Styshova, Margarita Monastyrnaya, Igor Dyachenko, Sergey Kozlov, Elena Leychenko   +9 more
doaj   +1 more source

Randomized Trial Evaluating Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema

Ophthalmology (Rochester, Minn.), 2010
Purpose To evaluate the safety and efficacy of intravitreal ranibizumab combined with prompt or deferred laser or intravitreal triamcinolone combined with prompt laser compared to laser alone for diabetic macular edema (DME).
M. Elman, L. P. Aiello, Roy W. Beck, N. Bressler, S. Bressler, A. R. Edwards, F. L. Ferris, S. Friedman, A. Glassman, K. Miller, I. Scott, Cynthia R. Stockdale, Jennifer K. Sun   +12 more
semanticscholar   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Bullous striae distensae in a nephrotic syndrome patient: First case report from the Middle East of a rare presentation and review of the literature

Clinical Case Reports
Striae distensae is a common cutaneous phenomenon that begins as reddish linear atrophic plaques (striae rubra) that over time progress to silvery‐white coloration (stria alba).
Sumayyah I. Alrefaie, Sarah B. Aljoudi, Houriah Y. Nukaly, Waseem K. ALHawasawi, Jehad O. Hariri   +4 more
doaj   +1 more source

Myocardial Edema and Prognosis in Amyloidosis.

Journal of the American College of Cardiology, 2018
BACKGROUND Prognosis in light-chain (AL) and transthyretin (ATTR) amyloidosis is influenced by cardiac involvement. ATTR amyloidosis has better prognosis than AL amyloidosis despite more amyloid infiltration, suggesting additional mechanisms of damage in
T. Kotecha, A. Martinez-Naharro, T. Treibel, Rohin Francis, S. Nordin, A. Abdelgadir, D. Knight, G. Zumbo, S. Rosmini, V. Maestrini, H. Bulluck, R. Rakhit, A. Wechalekar, J. Gilbertson, M. Sheppard, P. Kellman, J. Gillmore, J. Moon, P. Hawkins, M. Fontana   +19 more
semanticscholar   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Diabetic macular edema: Evidence-based management

Indian Journal of Ophthalmology, 2018
Diabetic macular edema (DME) is the most common cause of vision loss in patients with diabetic retinopathy with an increasing prevalence tied to the global epidemic in type 2 diabetes mellitus.
D. Browning, M. W. Stewart, Cho-Ping Lee
semanticscholar   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Periocular triamcinolone versus intravitreal triamcinolone versus intravitreal dexamethasone implant for the treatment of uveitic macular edema: The PeriOcular versus INTravitreal corticosteroids for uveitic macular edema (POINT) Trial

Ophthalmology (Rochester, Minn.), 2018
Objective: To evaluate the comparative effectiveness of three regional corticosteroid injections for uveitic macular edema: periocular triamcinolone acetonide (PTA), intravitreal triamcinolone acetonide (ITA), and the intravitreal dexamethasone implant ...
J. Thorne, E. Sugar, J. Holbrook, A. Burke, M. Altaweel, Albert T. Vitale, N. Acharya, J. Kempen, D. Jabs   +8 more
semanticscholar   +1 more source

Acute Hemorrhagic Edema of Infancy [PDF]

, 2016
Acute Hemorrhagic Edema of Infancy is a small vessel leucocytoclastic vasculitis affecting young infants. It is characterized by large, target-like, macular to purpuric plaques predominantly affecting the face, ear lobes and extremities.
Torre, ML, Garcia, C, Sokolova, A, Amaro, C   +3 more
core   +1 more source