Results 131 to 140 of about 53,894 (278)

Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy

Clinical Genetics, EarlyView.
Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen, Karen Grønskov, Line Kessel, Sarah Linea von Holstein, Lisbeth Birk Møller, Mette Kjøbæk Gundestrup Andersen, Marianne Søndergaard Khinchi, Steffen Hamann, Marianne Wegener, Mette Bertelsen   +9 more
wiley   +1 more source

Clinical outcomes of ranibizumab treatment in diabetic eye disease [PDF]

, 2015
Background: The vascular endothelial growth factor (VEGF) inhibitor ranibizumab is emerging as an efficacious treatment for diabetic macular oedema. Large clinical trials have shown improvements in visual acuity and reduced central retinal thickness ...
Comyn, OJ
core  

Intravitreal bevacizumab injections for diabetic macular edema – predictors of response: a retrospective study [PDF]

, 2016
Lavnish Joshi,1–3 Asaf Bar,4 Oren Tomkins-Netzer,1,3 Satish Yaganti,1 Jiten Morarji,1 Panayiotis Vouzounis,1 Sophie Seguin-Greenstein,1,4 Simon R Taylor,3,5 Sue Lightman1,3 1Department of Clinical Ophthalmology, UCL Institute of Ophthalmology and ...
Tomkins-Netzer O, Morarji J, Joshi L, Lightman S, Vouzounis P, Taylor SR, Seguin-Greenstein S, Bar A, Yaganti S   +8 more
core  

Health, hope and worry: A qualitative study of people with diabetes' experiences with anti‐VEGF treatment

Diabetic Medicine, EarlyView.
Abstract Aims Diabetic macular edema (DME) is a leading cause of vision loss among individuals with diabetes. While anti‐VEGF therapy is a widely used and effective treatment, limited research has explored participants' lived experiences throughout the treatment process.
J. K. Leksell, E. Granstam, T. Granström, E. Nerpin   +3 more
wiley   +1 more source

Etiology and treatment of the inflammatory causes of cystoid macular edema

Journal of Inflammation Research, 2009
Hyung Cho1, Assumpta Madu11Department of Ophthalmology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USAAbstract: Cystoid macular edema in its various forms can be considered one of the leading causes of central vision
Hyung Cho, Assumpta Madu
doaj  

Semaglutide Injection Once‐Weekly for Weight Management in Adults: Results From A Randomized Phase III, Active‐Controlled Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To evaluate and compare the efficacy, safety, and immunogenicity of a synthetic semaglutide injection (Test semaglutide) with Wegovy (Reference semaglutide) injection for weight management. Materials and Methods This randomized, Phase III, non‐inferiority study included adults with obesity or overweight with or without comorbidities from ...
Unnikrishnan Ambika Gopalakrishnan, Ameya Joshi, Harish Kumar, Richa Giri, Sanjiv Maheshwari, Valluri Satya Prasad, Jitendra Shukla, Rekha M. Chowdaiah, Nutan Kumar Agrawal, Yogesh Rasal, Banshidhar Sahoo, Shweta Bhandari, Ambanna Gowda, Uday Phadke, Pravin Supe, Niranjan Pathak, Ambrish Chandrappa, Ashutosh Sonawane, Yash Bahulikar, Amit Bhaskar, Arunkumar Radhakrishnan, Priyanka Yadav, Sucheta Pandit, Supriya Sonowal, Dipak Patil, Pravin Ghadge, Suyog Mehta   +26 more
wiley   +1 more source

Early Worsening of Diabetic Retinopathy Following Initiation of Hybrid Closed‐Loop/Automated Insulin Delivery Systems in Type 1 Diabetes: A Systematic Review and Structured Study‐Level Synthesis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Hybrid closed‐loop (HCL) systems achieve rapid, algorithm‐driven improvements in glycaemia in type 1 diabetes (T1D). Paradoxically, rapid improvement in glycaemic control is associated with early worsening of diabetic retinopathy (EWDR), a phenomenon established in the intensive insulin therapy era.
Matthew Anson, Ahmed Iqbal, Shazli Azmi, Philip Weston, Lucy Hughes, Mahreen Choudhury, David M. Hughes, Yalin Zheng, Philip I. Burgess, Uazman Alam   +9 more
wiley   +1 more source

Treatment costs of cystoid macular edema among patients following cataract surgery [PDF]

, 2016
Jordana K Schmier,1 David W Covert,2 Carolyn K Hulme-Lowe,1 Anmol Mullins,3 Emmanuel M Mahlis4 1Health Sciences, Exponent Inc., Alexandria, VA, 2Health Economics, 3Global Market Access, 4US Pharma Medical Affairs, Alcon Inc., Fort Worth, TX, USA ...
Mullins A, Mahlis EM, Schmier JK, Covert DW, Hulme-Lowe CK   +4 more
core  

Bilateral toxoplasma retinitis with vitreous hemorrhage and macular edema during immunosuppressive treatment [PDF]

A 54-year-old woman with a history of peripheral spondyloarthropathy for 10 years, treated with steroids and methotrexate, was hospitalized due to necrotic retinitis with arteritis of left eye.
Piotr Lasota
core   +1 more source

Afibercept treatment for macular edema with and without serous retinal detachment due to branch retinal vein occlusion. [PDF]

Arq Bras Oftalmol, 2023
Irgat SG, Özcura F.
europepmc   +1 more source