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Apparent Failure of Edetic Acid Chelation Therapy for the Treatment of Coronary Atherosclerosis
Patients diagnosed with incurable or fatal diseases may seek alternatives to standard medical therapy and spend significant amounts of money for these therapies. One alternative medical therapy, chelation therapy with edetic acid (EDTA), has gained considerable popularity for the alleged treatment of atherosclerotic vascular disease; however, its ...
S R, Wirebaugh, D R, Geraets
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To the Editor.— The Food and Drug Administration has recently stated that unless further information is made available regarding the efficacy of the oral form of edetate calcium disodium (EDTA) that after six months, this form will be removed from the market.
John H. Nodine
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Spectrophotometric Titration of Edetic Acid in Ophthalmic Solutions
Journal of Pharmaceutical Sciences, 1974The procedure described here is applicable for determining edetic acid (ethylenediaminetetraacetic acid) at the 0.05–0.2% level in ophthalmic solutions. This method employs a spectrophotometric titration, using a magnesium-ion solution as titrant and arsenazo I as the indicator.
E E, Kaminski, D M, Pacenti
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SYNERGISTIC EFFECT OF EDETIC-ACID/ANTIBIOTIC COMBINATIONS ON PSEUDOMONAS ÆRUGINOSA
Lancet, The, 1969Abstract The disodium salt of ethylenediamine-tetra-acetic acid (E.D.T.A., edetic) enhances the effect of penicillin G, ampicillin, tetracycline, and chloramphenicol on a resistant strain of Pseudomonas œruginosa. This effect is shown to be due to synergism of the E.D.T.A./antibiotic combinations.
A W Asscher
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The control of nitrilotriacetic acid in edetic acid and its salts by liquid chromatography
Journal of Pharmaceutical and Biomedical Analysis, 2003Two liquid chromatographic methods have been developed and validated for the determination of nitrilotriacetic acid (NTA) in edetic acid (EDTA) and its salts. In one method NTA and EDTA are separated on a polymer column without pretreatment, and are detected amperometrically using a glassy-carbon electrode.
G G Skellern
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Drug Transfer across Rat Intestinal Musculature after Edetic Acid Treatment
Journal of Pharmaceutical Sciences, 1971The columnar epithelium of the in vitro rat intestine was separated from the intestinal musculature by treatment with icecold edetic acid solution. The in vitro absorption kinetics through the denuded intestinal musculature for salicylate ion and acetanilide were followed in pH 7.4 sodium phosphate and potassium phosphate buffers, as well as in an ...
Leslie Z Benet, L Z Benet
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