Results 171 to 180 of about 4,622 (208)

Edetic Acid

open access: closed, 2007
S.J. Enna, David B. Bylund
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Drug Transfer across Rat Intestinal Musculature after Edetic Acid Treatment

Journal of Pharmaceutical Sciences, 1971
The columnar epithelium of the in vitro rat intestine was separated from the intestinal musculature by treatment with icecold edetic acid solution. The in vitro absorption kinetics through the denuded intestinal musculature for salicylate ion and acetanilide were followed in pH 7.4 sodium phosphate and potassium phosphate buffers, as well as in an ...
R K, Nayak, L Z, Benet
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EFFECTS OF ASCORBIC ACID AND DISODIUM EDETATE ON THE STABILITY OF ISOPRENALINE HYDROCHLORIDE INJECTION

Journal of Clinical Pharmacy and Therapeutics, 1984
Disodium edetate (0.01%), either alone or in combination with ascorbic acid (0.1%) was an effective stabilizer for isoprenaline injection B.P. but adjustment to pH 2.8 was necessary. The bubbling of nitrogen through the solution in the ampoule before sealing did not prevent degradation in unprotected solutions.
G, Smith, K, Hasson, J A, Clements
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Therapeutic efficacy of combined meso 2,3-dimercaptosuccinic acid and calcium disodium edetate treatment during acute lead intoxication in rats

Human & Experimental Toxicology, 1995
1 The therapeutic ability of Ca disodium EDTA and meso 2,3-dimercaptosuccinic acid (DMSA) was studied, both individually and when given in combination, in reducing lead concentration in blood and other soft tissues, and in restoring lead induced altered biochemical variables in acute lead intoxicated rats.2 Combined treatment with the above two ...
G J, Flora   +3 more
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Randomized Study of Minocycline and Edetic Acid as a Locking Solution for Central Line (Port-A-Cath) in Children with Cancer

Chemotherapy, 2011
<i>Background:</i> Contamination of central catheters is frequent, and biofilm perpetuates infections. Heparin does not protect against infections because it has no antibiotic action. Minocycline and edetic acid (M-EDTA), a potent calcium chelating agent that destroys bacterial and fungal cell membrane and disrupts biofilm, may be an ...
Julieta Maria, Ferreira Chacon   +7 more
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Comparative Evaluation of Disodium Edetate and Diethylenetriaminepentaacetic Acid as Iron Chelators to Prevent Metal -Catalyzed Destabilization of a Therapeutic Monoclonal Antibody

Journal of Pharmaceutical Sciences, 2010
Understanding the effect of metal chelators with respect to their ability to inhibit metal-catalyzed degradation in biologic products is a critical component for solution formulation development. Two metal chelators, disodium edetate (Na(2)EDTA) and diethylenetriaminepentaacetic acid (DTPA), were evaluated for their ability to stabilize IgG2 mAb in ...
Shuxia, Zhou   +8 more
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