Results 171 to 180 of about 4,622 (208)
Allergic reactions from edetic acid in apomorphine preparation
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Chelation with edetic acid should be considered before surgery
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Drug Transfer across Rat Intestinal Musculature after Edetic Acid Treatment
Journal of Pharmaceutical Sciences, 1971The columnar epithelium of the in vitro rat intestine was separated from the intestinal musculature by treatment with icecold edetic acid solution. The in vitro absorption kinetics through the denuded intestinal musculature for salicylate ion and acetanilide were followed in pH 7.4 sodium phosphate and potassium phosphate buffers, as well as in an ...
R K, Nayak, L Z, Benet
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Journal of Clinical Pharmacy and Therapeutics, 1984
Disodium edetate (0.01%), either alone or in combination with ascorbic acid (0.1%) was an effective stabilizer for isoprenaline injection B.P. but adjustment to pH 2.8 was necessary. The bubbling of nitrogen through the solution in the ampoule before sealing did not prevent degradation in unprotected solutions.
G, Smith, K, Hasson, J A, Clements
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Disodium edetate (0.01%), either alone or in combination with ascorbic acid (0.1%) was an effective stabilizer for isoprenaline injection B.P. but adjustment to pH 2.8 was necessary. The bubbling of nitrogen through the solution in the ampoule before sealing did not prevent degradation in unprotected solutions.
G, Smith, K, Hasson, J A, Clements
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Human & Experimental Toxicology, 1995
1 The therapeutic ability of Ca disodium EDTA and meso 2,3-dimercaptosuccinic acid (DMSA) was studied, both individually and when given in combination, in reducing lead concentration in blood and other soft tissues, and in restoring lead induced altered biochemical variables in acute lead intoxicated rats.2 Combined treatment with the above two ...
G J, Flora +3 more
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1 The therapeutic ability of Ca disodium EDTA and meso 2,3-dimercaptosuccinic acid (DMSA) was studied, both individually and when given in combination, in reducing lead concentration in blood and other soft tissues, and in restoring lead induced altered biochemical variables in acute lead intoxicated rats.2 Combined treatment with the above two ...
G J, Flora +3 more
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Chemotherapy, 2011
<i>Background:</i> Contamination of central catheters is frequent, and biofilm perpetuates infections. Heparin does not protect against infections because it has no antibiotic action. Minocycline and edetic acid (M-EDTA), a potent calcium chelating agent that destroys bacterial and fungal cell membrane and disrupts biofilm, may be an ...
Julieta Maria, Ferreira Chacon +7 more
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<i>Background:</i> Contamination of central catheters is frequent, and biofilm perpetuates infections. Heparin does not protect against infections because it has no antibiotic action. Minocycline and edetic acid (M-EDTA), a potent calcium chelating agent that destroys bacterial and fungal cell membrane and disrupts biofilm, may be an ...
Julieta Maria, Ferreira Chacon +7 more
openaire +2 more sources
Journal of Pharmaceutical Sciences, 2010
Understanding the effect of metal chelators with respect to their ability to inhibit metal-catalyzed degradation in biologic products is a critical component for solution formulation development. Two metal chelators, disodium edetate (Na(2)EDTA) and diethylenetriaminepentaacetic acid (DTPA), were evaluated for their ability to stabilize IgG2 mAb in ...
Shuxia, Zhou +8 more
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Understanding the effect of metal chelators with respect to their ability to inhibit metal-catalyzed degradation in biologic products is a critical component for solution formulation development. Two metal chelators, disodium edetate (Na(2)EDTA) and diethylenetriaminepentaacetic acid (DTPA), were evaluated for their ability to stabilize IgG2 mAb in ...
Shuxia, Zhou +8 more
openaire +2 more sources

