Results 111 to 120 of about 978,459 (257)

Deterministic Online Bipartite Edge Coloring

We study online bipartite edge coloring, with nodes on one side of the graph revealed sequentially. The trivial greedy algorithm is (2 — o (1))-competitive, which is optimal for graphs of low maximum degree, Δ = O (log n) [BNMN IPL’92].
Vintan, Radu, Svensson, Ola, Blikstad, Joakim, Svensson, O., Wajc, D., Vintan, R., Wajc, David, Blikstad, J., Svensson, Ola,, Wajc, David,, Blikstad, Joakim,, Vintan, Radu,   +11 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Distributed Edge Coloring and Locally Sparse Graph Coloring

, 2014
Graph coloring is a central problem in distributed computing. In this work, we study both the edge coloring and vertex coloring problems. For constant ɛ> 0, we give a distributed algorithm for (1 + ɛ)∆-edge coloring running in O(log ∗ log n ∆ · max(1,
Hsin-hao Su, Seth Pettie, Michael Elkin
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

THE LOCATING RAINBOW EDGE CONNECTION NUMBERS OF SOME GENERALIZED SUN GRAPHS

Barekeng
Throughout this paper, G denotes a finite, simple, connected, and undirected graph. The concept of the locating rainbow edge connection number is motivated by the concept of the locating rainbow connection number in which the coloring is assigned to ...
Muhammad Ahnaf Yusuf, A. N. M. Salman, Mukayis Mukayis   +2 more
doaj   +1 more source

Edge-Coloring and f-Coloring for Various Classes of Graphs

, 1999
In an ordinary edge-coloring of a graph each color appears at each vertex at most once. An f-coloring is a generalized edge-coloring in which each color appears at each vertex v at most f(v) times where f(v) is a positive integer assigned to v.
Xiao Zhou, Takao Nishizeki
core  

Asymmetric game perfect graphs and the circular coloring game of weighted graphs [PDF]

, 2011
Zacharopoulos P. Asymmetric game perfect graphs and the circular coloring game of weighted graphs.
Zacharopoulos, Panagiotis
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source