Results 111 to 120 of about 2,800 (259)
Transformations of edge-colourings of cubic graphs
AbstractIn this paper we shall study and describe all possible forms of the so-called change-graph which is the subgraph of a cubic graph G containing all the edges (and only the edges) having different colours in two different edge-colourings of G.
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The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
JUST CHROMATIC EXCELLENCE IN FUZZY GRAPHS
Abstaract−Let G be a simple fuzzy graph. A family Γf= {γ, γ2, . . . , γk} of fuzzy sets on a set V is called k-fuzzy colouring of V = (V, σ, µ) if i)∪Γf= σ, ii) γi∩ γj= ∅, iii)for every strong edge (x, y)(i.e., µ(xy) > 0) of G min{γi(x), γi(y)} = 0 ...
- Dharmalingam, Udaya Suriya
doaj
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Recent progress on edge-colouring graphs
Suppose G is a multigraph without loops. Let \(\chi\) '(G) and \(\Delta\) (G) denote respectively the chromatic index and the maximum degree of G. If \(\chi '(G)=\Delta (G)\), then G is said to be Class 1, and otherwise G is Class 2. A graph G is said to be overfull, if \(| E(G)| >\Delta (G)\lfloor | V(G)| \rfloor.\) This paper summarizes some of the ...
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MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source

