Results 171 to 180 of about 898,897 (299)

A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy

Advanced Science, EarlyView.
A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Yan Zhao, Yufei Lan, Min‐Goo Lee, Jinjun He, Yueran Pan, Eunji Kim, Xin Fu, Sungwook Jung, Wanxia Lu, Jinyue Fan, Haoxiang Chen, Yuanbo Zhao, Yuling Xu, Jong Seung Kim, Chao Zhang   +14 more
wiley   +1 more source

Beyond unit-level certification: An operational agenda for biodiversity-positive tropical production landscapes. [PDF]

iScience
Zwerts JA.
europepmc   +1 more source

Access, Obligation, and Resilience: Rule Bundles in Java's Forest-Edge Coffee Agroforestry

Medea Rahmadhani Utomo, Erekso Hadiwijoyo, Andrean Eka Hardana, Mofit Jamroni, Ajik Siswantoro, Anisa Aprilia   +5 more
openalex   +1 more source

Edge Bundling as a Multi-Objective Optimization Problem (Poster Abstract) [PDF]

Vieira, Raissa dos Santos, Nascimento, Hugo A. D. do, Ferreira, Joelma de Moura, Foulds, Les, Klein, Karsten, Schreiber, Falk   +5 more
openalex   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

Advanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun, Junhao Fan, Xiaolu Xie, Yuting Shi, Xiaoqing Liu, Tiefeng Xu, Sidi Yang, Keda Shi, Chengshu Xie, Shixiong Li, Siwen Chen, Ruoxi Cai, Ping He, Yuzhen Ye, Tao Chen, Xiancai Ma, Chunmei Li, Jingyou Yu, Deyin Guo   +18 more
wiley   +1 more source

Synergistic assembly, disassembly, and protection of complex forms of bundled F-actin. [PDF]

J Cell Biol
Rajan S, Yoon J, Wu H, Baskar R, Aguirre R, Terman JR, Reisler E.   +6 more
europepmc   +1 more source

Unravelling the Distinct Phenotype and Mechanosensitive Properties of Different Tendon Cell Populations

Advanced Science, EarlyView.
Tendon interfascicular and fascicular matrix cells are isolated and cultured, revealing distinct phenotypes and mechanosensitive responses. Interfascicular matrix cells exhibit marked stiffness‐dependent phenotypic plasticity, whereas fascicular matrix cells remain comparatively stable.
S. E. Grossemy, D. E. Zamboulis, N. S. Khatib, M. R. Fazal, C. C. Gains, A. Giannopoulos, T. Hopkins, C. Bevan, Y. Aggarwal, M. M. Knight, H. R. C. Screen   +10 more
wiley   +1 more source

Thermochemical Core–Shell Architecturing of Si‐SWCNT Composites for High‐Performance Li‐Ion Battery Anodes

Advanced Science, EarlyView.
A thermochemically engineered core–shell Si architecture is developed through the controlled evolution of a SWCNT‐coated Mg2Si precursor. The process simultaneously generates a nanoporous Si shell for strain accommodation and Li+ transport, a chemically anchored SiC interfacial layer for robust mechanical and electrical coupling, and a Mg‐containing Si
Dong Gyun Hong, Byeong Guk Kim, Jung‐Hyeok Park, Sunwoo Lee, Donghwi Cho, Jaeik Hyun, Ki‐Hun Nam, Youngoh Kim, Geon‐Woong Lee, Sunhye Yang, Seung Yol Jeong, Myungwoo Choi   +11 more
wiley   +1 more source

Efficient uncertainty aware human activity recognition on microcontrollers using hyperdimensional computing and conformal prediction. [PDF]

Sci Rep
Lamaakal I, Yahyati C, Maleh Y, El Makkaoui K, Ouahbi I.   +4 more
europepmc   +1 more source

When the Link Is the Variable: Delay-Tolerant Networking and Bundle Custody Transfer at the C5ISR Edge

Justin H. Kuiper
openalex   +2 more sources