Results 51 to 60 of about 5,076 (252)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Clinical characteristics and risk factors of an outbreak with scrub typhus in previously unrecognized areas, Jiangsu province, China 2013.

PLoS ONE, 2015
Scrub typhus, caused by Orientia tsutsugamushi, has emerged recently in Jingjiang City, China where the disease had not been known to exist. We analyzed epidemiological data, clinical characteristics and risk factors of scrub typhus outbreak in Jingjiang
Jianli Hu, Zhongming Tan, Dafei Ren, Xiang Zhang, Yilin He, Changjun Bao, Dapeng Liu, Qianhua Yi, Weijuan Qian, Jun Yin, Zhen Xu, Chunxia Yu, Shenjiao Wang, Bin Wu, Haiyu Yang, Ming Yue, Yun Zhang, Wendong Liu, Yefei Zhu, Minghao Zhou, Fenyang Tang   +20 more
doaj   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Attribute-Driven Edge Bundling for General Graphs with Applications in Trail Analysis [PDF]

, 2015
International audienceEdge bundling methods reduce visual clutter of dense and occluded graphs. However, existing bundling techniques either ignore edge properties such as direction and data attributes, or are otherwise computationally not scalable ...
Telea, Alexandru, Vsevolod Peysakhovich, Christophe Hurter, Peysakhovich, Vsevolod, Hurter, Christophe, Alexandru Telea   +5 more
core   +2 more sources

The edge fault-diameter of Cartesian graph bundles

European Journal of Combinatorics, 2009
The Cartesian product of two graphs \(G_1\) and \(G_2\), \(G_1\square G_2\), has vertex set set \(V(G_1)\times V(G_2)\). Two vertices \((u_1, v_1)\) and \((u_2, v_2)\) are adjacent in \(G_1\square G_2\) if either \(u_1u_2\in E(G_1)\) and \(v_1=v_2\) or \(v_1v_2\in E(G_2)\) and \(u_1=u_2\). A graph \(G\) is a Cartesian graph bundle with fibre graph \(F\)
Iztok Banic, Rija Erves, Janez Zerovnik
openaire   +3 more sources

Field Report from Collaborative Research Center 1625: Heterogeneous Research Data Management Using Ontology Representations

Advanced Engineering Materials, EarlyView.
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed, Samuel García Vázquez, Behnam Mardani, Victor Dudarev, Alfred Ludwig, Maribel Acosta, Markus Stricker   +6 more
wiley   +1 more source

A Data Model and Method Framework for Cyberspace Map Visualization

ISPRS International Journal of Geo-Information
Integrating cyberspace and geographic space through map visualization is a valuable approach for revealing distribution patterns and relational dynamics in cyberspace. The interdisciplinary integration of network science and geographic science has gained
Zheng Zhang, Chenghu Zhou, Minjie Chen, Yibing Cao, Shaojing Fan   +4 more
doaj   +1 more source

MLSEB: Edge Bundling Using Moving Least Squares Approximation

, 2017
Edge bundling methods can effectively alleviate visual clutter and reveal high-level graph structures in large graph visualization. Researchers have devoted significant efforts to improve edge bundling according to different metrics. As the edge bundling
Wu, Jieting, Zhu, Feiyu, Yu, Hongfeng, Zeng, Jianping, Hongfeng Yu, Jieting Wu, Jianping Zeng, Feiyu Zhu   +7 more
core   +1 more source

Additive Manufacturing of Continuous Fibre Reinforced Composites: Process, Characterisation, Modelling, and Sustainability

Advanced Engineering Materials, EarlyView.
Additive manufacturing provides precise control over the placement of continuous fibres within polymer matrices, enabling customised mechanical performance in composite components. This article explores processing strategies, mechanical testing, and modelling approaches for additive manufactured continuous fibre‐reinforced composites.
Cherian Thomas, Amir Hosein Sakhaei
wiley   +1 more source