Results 121 to 130 of about 1,425,497 (376)

The Relaxed Game Chromatic Index of \u3cem\u3ek\u3c/em\u3e-Degenerate Graphs [PDF]

, 2007
The (r, d)-relaxed coloring game is a two-player game played on the vertex set of a graph G. We consider a natural analogue to this game on the edge set of G called the (r, d)-relaxed edge-coloring game. We consider this game on trees and more generally,
Dunn, Charles
core   +1 more source

Properly Edge-colored Theta Graphs in Edge-colored Complete Graphs [PDF]

Graphs and Combinatorics, 2018
With respect to specific cycle-related problems, edge-colored graphs can be considered as a generalization of directed graphs. We show that properly edge-colored theta graphs play a key role in characterizing the difference between edge-colored complete graphs and multipartite tournaments.
Ruonan Li, Ruonan Li, Shenggui Zhang, Hajo Broersma   +3 more
openaire   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Twin edge colorings of certain square graphs and product graphs

Electronic Journal of Graph Theory and Applications, 2016
A twin edge $k\!$-coloring of a graph $G$ is a proper edge $k$-coloring of $G$ with the elements of $\mathbb{Z}_k$ so that the induced vertex $k$-coloring, in which the color of a vertex $v$ in $G$ is the sum in $\mathbb{Z}_k$ of the colors of the edges ...
R Rajarajachozhan, R. Sampathkumar
doaj   +1 more source

Strong chromatic index of sparse graphs [PDF]

, 2013
A coloring of the edges of a graph $G$ is strong if each color class is an induced matching of $G$. The strong chromatic index of $G$, denoted by $\chi_{s}^{\prime}(G)$, is the least number of colors in a strong edge coloring of $G$.
Dębski, Michał, Grytczuk, Jarosław, Śleszyńska-Nowak, Małgorzata   +2 more
core  

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Solution of Vizing's Problem on Interchanges for Graphs with Maximum Degree 4 and Related Results [PDF]

, 2014
Let $G$ be a Class 1 graph with maximum degree $4$ and let $t\geq 5$ be an integer. We show that any proper $t$-edge coloring of $G$ can be transformed to any proper $4$-edge coloring of $G$ using only transformations on $2$-colored subgraphs (so-called ...
Asratian, Armen S., Casselgren, Carl Johan   +1 more
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source