Results 81 to 90 of about 978,529 (303)
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Edge coloring signed graphs [PDF]
31 pages, 13 ...
openaire +3 more sources
Tight Bounds for Online Edge Coloring
Vizing's celebrated theorem asserts that any graph of maximum degree Delta admits an edge coloring using at most Delta + 1 colors. In contrast, Bar-Noy, Motwani and Naor showed over a quarter century ago that the trivial greedy algorithm, which uses 2 ...
Peng, Binghui +5 more
core +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
List Star Edge-Coloring of Subcubic Graphs [PDF]
A star edge-coloring of a graph G is a proper edge coloring such that every 2-colored connected subgraph of G is a path of length at most 3. For a graph G, let the list star chromatic index of G, ch′st(G), be the minimum k such that for any k-uniform ...
Kostochka Alexandr +8 more
core +2 more sources
Twin edge colorings of certain square graphs and product graphs
A twin edge $k\!$-coloring of a graph $G$ is a proper edge $k$-coloring of $G$ with the elements of $\mathbb{Z}_k$ so that the induced vertex $k$-coloring, in which the color of a vertex $v$ in $G$ is the sum in $\mathbb{Z}_k$ of the colors of the edges ...
R Rajarajachozhan, R. Sampathkumar
doaj +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Vertex Coloring Edge-Weighting of Coronation by Path Graphs [PDF]
In this paper, we study vertex coloring edge of corona graph. A k-edge weigting of graph G is mapping w : (EG) ! f1; 2; ; kg. An edge-weighting w induces a vertex coloring Fw : V (G) ! N de ned by fw(v) = P v2e w(e).
KRISTIANA, Arika Indah +5 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

