A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
LeafAI: Interpretable plant disease detection for edge computing. [PDF]
Al Kafi MA +5 more
europepmc +1 more source
IEEE Access Special Section Editorial: Recent Advances in Computational Intelligence Paradigms for Security and Privacy for Fog and Mobile Edge Computing [PDF]
Brij B. Gupta +4 more
openalex +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Low-Light Image Segmentation on Edge Computing System. [PDF]
Choi SC, Kim SY.
europepmc +1 more source
Optimization Technique of the Philippine Army Warehousing and Inventory System (PAWIS) Using Cloud and Edge Computing: Development of a Strategic Framework for All Units [PDF]
Cherry D. Casuat +5 more
openalex +1 more source
COVID-19 Networking Demand: An Auction-Based Mechanism for Automated Selection of Edge Computing Services [PDF]
Abdulsalam Yassine, M. Shamim Hossain
openalex +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Ensemble deep learning approach for traffic video analytics in edge computing. [PDF]
Sathyamoorthy M +3 more
europepmc +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source

