Results 61 to 70 of about 323,476 (264)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Quality Evaluation for Edge Detection of Chromosome G-band Images for Segmentation [PDF]

Applied Medical Informatics, 2013
Edge detection of chromosome in G-band type image is an important preprocessing step in segmentation. A chromosome type G-band image is generally very noise and poor image quality, lack of contrast and hold in image.
Natthariya LAOPRACHA, Pichet WAYALUN, Phatthanaphon WANCHANTHUEK, Panida SONGRUM   +3 more
doaj  

Research on the algorithm of sub-pixel edge detection without rough localization

上海师范大学学报. 自然科学版, 2016
Concerning the traditional sub-pixel edge detection techniques need to use the traditional edge detection algorithms for coarse positioning before precision positioning the algorithm of sub-pixel edge detection without rough localization was proposed ...
XIA Yangyang, LIN Jing
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Adaptive Ant Colony Optimization on Mango Classification Using K-Nearest Neighbor and Support Vector Machine

Journal of Information Systems Engineering and Business Intelligence, 2017
— Leaves recognition can use an image edge detection method. In this research, the classification of mango gadung and manalagi will be performed. In the preprocess stage edge detection method using adaptive ant colony optimization method.
Febri Liantoni, Luky Agus Hermanto
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Cloud-Edge Collaborative Inference-Based Smart Detection Method for Small Objects

Modelling
Emerging technologies are revolutionizing power system operation and maintenance. Intelligent state perception is pivotal for stable grid operation, with small object detection technology being vital for identifying minor hazards in power facilities ...
Cong Ye, Shengkun Li, Jianlei Wang, Hongru Li, Xiao Li, Sujie Shao   +5 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Robust edge-detection algorithm for runway edge detection

SPIE Proceedings, 2008
Fog and other poor visibility conditions hamper the visibility of runway surfaces and any obstacles present on the runway, potentially creating a situation where a pilot may not be able to safely land the aircraft. Assisting the pilot to land the aircraft safely in such conditions is an active area of research.
Swathi Tandra, Zia-ur Rahman
openaire   +3 more sources