Results 71 to 80 of about 1,161,259 (282)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Quantum Spin Hall Effect in Graphene

open access: yes, 2005
We study the effects of spin orbit interactions on the low energy electronic structure of a single plane of graphene. We find that in an experimentally accessible low temperature regime the symmetry allowed spin orbit potential converts graphene from an ...
C. L. Kane, E. J. Mele, N. B. Brandt
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Three‐dimensional transesophageal echocardiography‐guided transseptal puncture for percutaneous mitral valve edge‐to‐edge repair post‐percutaneous atrial septal defect closure

open access: yesClinical Case Reports, 2023
Key Clinical Message Three‐dimensional multiplanar analysis and real‐time three‐dimensional guidance using transesophageal echocardiography can help to identify and access the ideal position for transseptal puncture even in the presence of atrial septal ...
Hiroyuki Tabata   +3 more
doaj   +1 more source

Symbolic powers of edge ideals

open access: yesJournal of Algebra, 2004
Given a (finite simple) graph \(G\) with vertex set \(\{X_1,\dots, X_n\}\), a set of indeterminates generating the polynomial ring \(R= k[X_1,\dots, X_r]\), the ideal \(I(G)= (\{X_iX_j|\, X_i\) adjacent to \(X_j\})\) and the ring \(R/I(G)\) becomes of interest in the setting of commutative algebra/algebraic geometry as well as graph theory, since it is
openaire   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Optimal Scale Edge Detection Utilizing Noise within Images [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2003
Edge detection techniques have common problems that include poor edge detection in low contrast images, speed of recognition and high computational cost. An efficient solution to the edge detection of objects in low to high contrast images is scale space
Adnan Khashman
doaj  

Graph connectivity and binomial edge ideals

open access: yesProceedings of the American Mathematical Society, 2016
We relate homological properties of a binomial edge ideal $\mathcal{J}_G$ to invariants that measure the connectivity of a simple graph $G$. Specifically, we show if $R/\mathcal{J}_G$ is a Cohen-Macaulay ring, then graph toughness of $G$ is exactly $\frac{1}{2}$.
Banerjee, Arindam   +1 more
openaire   +3 more sources

Edge Ideals: Algebraic and Combinatorial Properties [PDF]

open access: yes, 2012
Let C be a clutter and let I(C) be its edge ideal. This is a survey paper on the algebraic and combinatorial properties of R/I(C) and C, respectively. We give a criterion to estimate the regularity of R/I(C) and apply this criterion to give new proofs of some formulas for the regularity.
Morey, Susan, Villarreal, Rafael H.
openaire   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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