Results 71 to 80 of about 1,118,707 (279)
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The -annihilating-ideal hypergraph of commutative ring
The concept of the annihilating-ideal graph of a commutative ring was introduced by Behboodi et. al in 2011. In this paper, we extend this concept to the hypergraph for which we define an algebraic structure called -annihilating-ideal of a commutative ...
K. Selvakumar, V. Ramanathan
doaj +2 more sources
Book illustrator in the context of his epoch: art heritage of Niwa Tokei (1760-1822)
The paper examines the art heritage of Niwa Tōkei (1760-1822) - an ukiyo-e book illustrator from Osaka - in terms of historical, social, and local peculiarities of his life and epoch.
Maria M. Kikteva
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Sequentially Cohen-Macaulay edge ideals [PDF]
Let G G be a simple undirected graph on
Francisco, Christopher A. +1 more
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Edge ideals and DG algebra resolutions
Let R = S/I where S = k[T_1, . . . , T_n] and I is a homogeneous ideal in S. The acyclic closure R<Y> of k over R is a DG algebra resolution obtained by means of Tate’s process of adjoining variables to kill cycles.
Adam Boocher +4 more
doaj
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The $\mathrm{v}$-Number of Binomial Edge Ideals [PDF]
The invariant $\mathrm{v}$-number was introduced very recently in the study of Reed-Muller-type codes. Jaramillo and Villarreal (J Combin. Theory Ser. A 177:105310, 2021) initiated the study of the $\mathrm{v}$-number of edge ideals.
Sengupta, Indranath +2 more
core +1 more source

