Results 51 to 60 of about 189,025 (287)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Kane-Mele with a twist: Quasicrystalline higher-order topological insulators with fractional mass kinks

open access: yesPhysical Review Research, 2020
We establish an analytic low-energy theory describing higher-order topological insulator (HOTI) phases in quasicrystalline systems. We apply this to a model consisting of two stacked Haldane models with oppositely propagating edge modes, analogous to the
Stephen Spurrier, Nigel R. Cooper
doaj   +1 more source

Three-dimensional edge waves in plates [PDF]

open access: yes, 2007
This paper describes the propagation of three-dimensional symmetric waves localized near the traction-free edge of a semi-infinite elastic plate with either traction-free or fixed faces.
Kaplunov, JD, Zernov, V
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Spatiotemporal forecasting of the edge localized modes in tokamak plasmas using neural networks

open access: yesMachine Learning: Science and Technology
Artificial intelligence techniques have been increasingly adopted by the plasma and fusion science to address problems like plasma reconstruction, surrogate modeling, and tokamak/stellarator optimization.
Anirban Samaddar   +9 more
doaj   +1 more source

Inter-ELM pedestal localized fluctuations in tokamaks: Summary of multi-machine observations

open access: yesNuclear Materials and Energy, 2019
A variety of experimental studies on pedestal localized fluctuations appearing in between crashes of edge localized modes (ELMs) across several tokamaks have been reviewed and summarized.
F.M. Laggner   +3 more
doaj   +1 more source

Localized modes in defective multilayer structures

open access: yes, 2009
In this paper, the localized surface modes in a defective multilayer structure has been investigated. It is shown that the defective multilayer structures can support two different kind of localized modes depending on the position and the thickness of ...
A. Namdar   +5 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Witnessing edge modes in trimerized circuit quantum electrodynamic lattice

open access: yesNew Journal of Physics
We propose a scheme to investigate and witness edge modes of general one-dimensional photonic trimers in a circuit quantum electrodynamic lattice. These in-gap edge modes are strictly and analytically solved and the criteria for their emergence are ...
Xuedong Zhao   +5 more
doaj   +1 more source

Topological bands and localized vibration modes in quasiperiodic beams

open access: yesNew Journal of Physics, 2019
We investigate a family of quasiperiodic continuous elastic beams, the topological properties of their vibrational spectra, and their relation to the existence of localized modes.
Raj Kumar Pal   +2 more
doaj   +1 more source

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