Results 71 to 80 of about 190,088 (285)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Transport and acceleration mechanism of fast ions during edge localized modes in ASDEX Upgrade

Nuclear Fusion, 2023
Observations of enhanced fast-ion losses during edge localized modes (ELMs) have been reported in the ASDEX Upgrade tokamak, revealing losses above the injection energy. This suggests that fast ions can be accelerated and lost due to the ELMs.
J.F. Rivero-Rodríguez, J. Galdon-Quiroga, J. Domínguez-Palacios, M. García-Muñoz, D. Garcia-Vallejo, J. Gonzalez-Martin, K.G. McClements, L. Sanchís, K. Särkimäki, A. Snicker, Y. Todo, L. Velarde, E. Viezzer, the ASDEX Upgrade Team   +13 more
doaj   +1 more source

Edge states in bilayer graphene in a magnetic field

, 2013
Edge states in biased bilayer graphene in a magnetic field are studied within the four-band continuum model. The analysis is done for the semi-infinite graphene plane and for the graphene ribbon of a finite width, in the cases of zigzag and armchair ...
Pyatkovskiy, P. K.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Progress towards edge-localized mode suppression via magnetic perturbations in hydrogen plasmas

Nuclear Fusion
The suppression of edge-localized modes (ELMs) by applying resonant magnetic perturbations (RMPs) is well studied in low collisionality deuterium plasmas as a measure to reduce transient divertor heat loads.
N. Leuthold, W. Suttrop, C. Paz-Soldan, M.G. Dunne, R. Fischer, E. Hinson, M. Knolker, F. Laggner, N.C. Logan, T. Osborne, D. Orlov, L. Schmitz, M. Shafer, M. Willensdorfer, the ASDEX Upgrade Team, the EUROfusion MST1 Team   +15 more
doaj   +1 more source

The effect of the plasma response on peeling–ballooning modes during edge localized modes mitigated by resonant magnetic perturbations

Nuclear Fusion, 2023
The effects of resonant magnetic perturbation (RMP) fields on peeling–ballooning (P–B) modes are studied with the experimental equilibria of EAST based on the four-field model in BOUT++ code.
L.K. Dong, S.Y. Chen, M.L. Mou, Y. Luo, C.C. Qin, C.J. Tang   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Non-ideal MHD analysis of pedestal scans of AUG and JET

Nuclear Fusion
The extended MHD code CASTOR3D is used to perform the MHD stability analysis of predictive pedestal scans of standard ASDEX Upgrade and JET-ILW scenarios.
F. Stefanelli, M.G. Dunne, J. Puchmayr, H. Zohm   +3 more
doaj   +1 more source

Self-trapping and stable localized modes in nonlinear photonic crystals

, 2001
We predict the existence of stable nonlinear localized modes near the band edge of a two-dimensional reduced-symmetry photonic crystal with a Kerr nonlinearity.
A. A. Helmy, A. A. Maradudin, A. De Rossi, A. J. Sievers, A. J. Ward, A. R. McGurn, B. I. Swanson, C. M. Anderson, C. M. Anderson, C. M. de Sterke, D. N. Christodoulides, E. Trias, E. W. Laedke, E. W. Laedke, H. S. Eisenberg, I. V. Barashenkov, J. D. Joannoupoulos, K. Busch, M. Scalora, N. Aközbek, P. Binder, P. L. Christiansen, P. Millar, P. Tran, S. F. Mingaleev, S. Flach, S. Flach, S. John, S. Shoji, Serge F. Mingaleev, U. T. Schwarz, V. K. Mezentsev, V. N. Astratov, W. Chen, Yu. B. Gaididei, Yu. S. Kivshar, Yuri S. Kivshar   +36 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source